10 results
Multiple Sclerosis - Summary

Multiple Sclerosis (MS) is an autoimmune-mediated neurodegenerative disease of the central nervous system
Multiple Sclerosis (MS ... neurodegenerative disease ... nearly 3:1 • MS ... criteria for MS ... #treatment #MS
McDonald Criteria for Diagnosis of Multiple Sclerosis
 • 2 or more attacks, 2 or more lesions
McDonald Criteria for Diagnosis ... year of disease ... McDonald #Criteria #Diagnosis ... Multiple #Sclerosis #MS ... #neurology
Low Alkaline Phosphatase - Hypophosphatasia 

Is Low Alkaline Phosphatase Of Clinical Importance?

ALP enzyme- Discovered in 1923
Low
Most cases diagnosed ... Malnutrition • Wilson's disease ... collection with EDTA Pathophysiology ... mineralization Symptoms ... respiratory failure • Neurologic
BEE Syndromes - Non-inflammatory Causes

Immune-mediated conditions affecting the Brain, Eye, and Ear

Visual or auditory symptoms in
Visual or auditory symptoms ... conjunction with symptoms ... and less common diseases ... consistent with MS ... BEE #Syndromes #neurology
Transverse Myelitis Overview

Focal inflammatory disorder of the spinal cord resulting in rapid onset of weakness, sensory
10-33% develop MS ... monophasic Pathophysiology ... swollen, while in MS ... Predictive of MS ... Multiple sclerosis (MS
Posterior Reversible Encephalopathy Syndrome (PRES) Overview

Clinico-Radiological Syndrome, characterized by:
 • Headache
 • Seizures
 • Altered mental
may precede the neurologic ... Shock, Autoimmune disease ... Etiology: • Pathophysiology ... Neurological symptoms ... #management #neurology
Hearing Loss - Differential Diagnosis Framework

Hearing Loss Types:
• Conductive
• Sensorineural
• Mixed
Presbycusis is the most common type
- Differential Diagnosis ... include a: • Neurologic ... Normal: Air > bone ... hearing loss: Bone ... Noise trauma ○ MS
Paget’s Disease: Complications
Abnormal Osteoclasts cause excessive bone turnover -> Incr bone resorption, Incr (abnormal) bone formation

MSK
Paget’s Disease: ... formation MSK ... PagetsDisease #pathophysiology ... #diagnosis #signs ... #symptoms #complications
Adhesive Capsulitis (Frozen Shoulder) - Pathogenesis and Clinical Findings

 • Primary (Idiopathic): Unknown etiology, but associated
mellitus, thyroid disease ... inflamed, usually in one ... FrozenShoulder #pathophysiology ... #diagnosis #symptoms ... stages #staging #msk
A quick infographic on various pearls about atopic dermatitis, a disease with an increasing burden on
dermatitis, a disease ... medications #treatment #diagnosis ... Chinellato I, Boner ... /hyperactivity symptoms ... Pedersen MS, Benros