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differential management dermatology hematology oncology signs treatment workup algorithm alkaline central clinical hepatology low pathophysiology peripheral phosphatase secondary staging syndrome
Alkaline Phosphatase (ALP) Elevation - Differential Diagnosis Algorithm ALP: - Enzymes that catalyze hydrolysis of organic phosphate
- Differential Diagnosis ... Intestine - Other causes ... Most common symptoms ... - Bone symptoms ... duct stricture/Stones
Causes of Thrombocytopenia and Platelet Disorders - Differential Diagnosis and Workup History: - Prior platelet count, family
- Differential Diagnosis ... pylori test (GI symptoms ... (CVID, WAS), (neurologic ... candidate) - Bone ... not required in all
Low Alkaline Phosphatase - Hypophosphatasia Is Low Alkaline Phosphatase Of Clinical Importance? ALP enzyme- Discovered in 1923 Low
Most cases diagnosed ... Malnutrition • Wilson's disease ... mineralization Symptoms ... respiratory failure • Neurologic ... Phosphatase: • Other causes
Paget’s Disease: Complications Abnormal Osteoclasts cause excessive bone turnover -> Incr bone resorption, Incr (abnormal) bone formation MSK
Paget’s Disease: ... formation MSK ... Nerve Palsies • Disordered ... pathophysiology #diagnosis ... #signs #symptoms
Causes of Peripheral and Central Vertigo PERIPHERAL VERTIGO 1. Benign paroxysmal positional vertigo (BPPV) - Short-lived (typically less
Causes of Peripheral ... Vascular disorders ... the headache (in one ... between ages of ... #differential #diagnosis
Osgood-Schlatter Disease - MSK Radiology Imaging Findings: • Infrapatellar fat-pad edema with loss of the patellar tendon
- MSK Radiology ... fragmentation and mild bone ... DOES NOT OSD in all ... tear (similar symptoms ... #msk
Causes of Hypomagnesemia • Redistribution: IV glucose, Correction of diabetic ketoacidosis, IV hyperalimentation, Refeeding after starvation,
Causes of Hypomagnesemia ... Tubulointerstitial renal disease ... ) • Endocrine disorders ... Hypercalcemic states ... #differential #diagnosis
Adhesive Capsulitis (Frozen Shoulder) - Pathogenesis and Clinical Findings • Primary (Idiopathic): Unknown etiology, but associated
with autoimmune disorders ... mellitus, thyroid disease ... a stroke that caused ... #symptoms #signs ... #msk
Hearing Loss - Differential Diagnosis Framework Hearing Loss Types: • Conductive • Sensorineural • Mixed Presbycusis is the most common type
- Differential Diagnosis ... include a: • Neurologic ... Normal: Air > bone ... hearing loss: Bone ... Mitochondrial disorders
Causes of Secondary Hypertension - Workup and Differential Diagnosis Approach (when evaluation should be done): 1. Severe or
and Differential Diagnosis ... evaluation should be done ... Stage 2 hypertension ... Renal parenchymal disease ... Neurologic disorders
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