54 results
Stress Fracture: Pathogenesis and clinical findings
Abnormal biomechanics, Repetitive impact activities
=> Repetitive subthreshold mechanical loading
=> Bone strain
=>
Pathogenesis and clinical ... mechanical loading => Bone ... strain => Bone ... pathophysiology #symptoms ... #signs
Scarf Sign (Normal) on Physical Exam

The scarf sign is used to assess developmental age and muscle
age and muscle tone ... infant with normal tone ... #clinical #video ... hypotonia #hypotonic #peds ... #pediatrics #tone
Prader-Willi Syndrome: Pathogenesis and clinical findings
 • Maternal uniparental disomy: inheriting 2 copies of maternal chromosome
Pathogenesis and clinical ... Prader-Willi Syndrome Signs ... /Symptoms/Complications ... Infertility • Decr Bone ... pathophysiology #peds
Osteoarthritis (OA): Clinical findings
 • Stimulation of joint nociceptors in subchondral bone -> Pain with loading
Osteoarthritis (OA): Clinical ... in subchondral bone ... contact between bony ... pathophysiology #diagnosis #signs ... #symptoms #complications
Pott's Disease in Tuberculosis - Diagnosis and Management Summary
Epidemiology:
 - Typically from TB endemic areas
 -
extrapulmonary cases Clinical ... Signs/Symptoms: ... years - May have signs ... of bacilli to bone ... CXR should be done
Osteosarcoma 
Most common primary malignant bone tumor in children 
Most Common Sites of Involvement:
1. Distal femur
primary malignant bone ... proximal femur Clinical ... injury • Systemic symptoms ... Features #Oncology #Peds
Retinoblastoma: Pathogenesis and clinical findings
 • Sporadic mutation -> One allele of RB1 tumor suppressor gene
Pathogenesis and clinical ... Sporadic mutation -> One ... gene mutated in one ... Inherited mutation -> One ... #symptoms
Spondylolysis & Spondylolisthesis: Pathogenesis and Clinical Findings

Pars interarticularis stress fracture (spondylolysis) - most frequently in the
Pathogenesis and Clinical ... tenderness • Positive one-legged ... XR — scotty dog sign ... pathophysiology #signs ... #symptoms
Mastoiditis: Pathogenesis and clinical findings

Acute or Chronic Otitis Media -> 
Stage 1: Hyperemeia of the mastoid
Pathogenesis and clinical ... 3: Necrosis of bone ... inner cortical bone ... pathophysiology #signs ... #symptoms #diagnosis
Gaucher Disease 

Pathophsiology
 • Lysosomal storage disorder
 • Deficiency of ß-glucocerebrosidase
• Accumulation of glucosylceramide in macrophages
Diagnosis
in GBA1 gene Clinical ... Osteonecrosis, bone ... Disease #Diagnosis #Signs ... #Symptoms