11 results
Vasospastic (Prinzmetal) Angina
Definition / Epidemiology:
 • Rest angina attributed to coronary artery vasospasm.
 • Patients often
younger than other ACS ... Pathophysiology: ... and sympathetic tone ... • Normal exercise ... #management
Posterior Reversible Encephalopathy Syndrome (PRES) Overview

Clinico-Radiological Syndrome, characterized by:
 • Headache
 • Seizures
 • Altered mental
Transplantation including bone ... Etiology: • Pathophysiology ... circulation: MCA ACA ... Seizures: Treat with AEDs ... #diagnosis #management
Guillain-Barré Syndrome (GBS)
Acute autoimmune demyelinating polyradiculoneuropathy that presents with rapidly progressive flaccid weakness
Epidemiology:
 • Incidence: 1
Guillain-Barré Syndrome ... protein with a normal ... - Of note, normal ... the underlying pathophysiology ... #diagnosis #management
Guillain-Barre Syndrome - Summary

Acute AIDP that presents with rapidly progressive flaccid weakness

Epidemiology:
 • 1-2 cases/100,000 per
Guillain-Barre Pathophysiology ... complete paralysis of all ... Guillain-Barre Diagnosis ... CSF PROTEIN - NORMAL ... #diagnosis #management
Differentiation Syndrome in APML
Epidemiology:
 • Incidence: common in APL (2-48% depending on the study)
 • Triggers:
Differentiation Syndrome ... Incidence: common in APL ... ATRA treatment Pathophysiology ... 500 mg QD until normal ... #management #hematology
Stiff Person Syndrome (SPS) - Diagnosis and Management Summary

Epidemiology:
 • Prevalence: 1-2 cases per million -
and Management ... Pathophysiology ... autoimmune response gone ... Oligoclonal bands • Normal ... #Management #treatment
Paraproteinemias

Entities That Can Feature A Monoclonal Protein/M Component:
• MM
• WM
• MGUS
• MGCS
• MGRS
• Splenic Marginal Zone
Splenic Marginal Zone ... Cryoglobulinemic, Hypo/normo-complementemic ... Evans • ITP • Cl-NH ... Thrombosis in vascular beds-renal ... #Differential #Diagnosis
Peripartum Cardiomyopathy - Summary
1. Definition
 • Towards the end of pregnancy to 5 months postpartum
Differential Diagnosis ... sx overlap with normal ... counseling should be done ... on diagnosis or ... teratogenic GDMT meds
The Neurological Evaluation of a Comatose Patient

Definition:
 • Coma: a state of unresponsiveness; the absence of
Differential Diagnosis ... • Locked-in syndrome ... • Mutism Pathophysiology ... movements; also normal ... stimulation to all
Preoperative Risk Evaluation

Major Pre-Op Questions:
1. Does the patient have any modifiable risk factors that could be
neuroexam - Oral ... Cataract Plan for Meds ... HgbA1c - if not done ... medical and surgical management ... stratification #diagnosis