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hematology differential differentiation management mds monoclonal myelodysplasia myelodysplastic paraproteinemias syndromes
Myelodysplastic Syndromes (MDS) What? Myelodysplastic syndromes are a group of disorders caused by blood cells that are poorly
transformation to AML ... cell types are abnormal ... cells might look abnormal ... blood cells appear normal ... progression to AML
Differentiation Syndrome in APML Epidemiology: • Incidence: common in APL (2-48% depending on the study) • Triggers:
Differentiation Syndrome ... Incidence: common in APL ... 500 mg QD until normal ... #APML #diagnosis ... management #hematology #oncology
Paraproteinemias Entities That Can Feature A Monoclonal Protein/M Component: • MM • WM • MGUS • MGCS • MGRS • Splenic Marginal Zone
Cryoglobulinemic, Hypo/normo-complementemic ... Evans • ITP • Cl-NH ... Thrombosis in vascular beds-renal ... #Differential #Diagnosis ... #Oncology
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