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diagnosis hematology differential management oncology algorithm causes anemia chronic cll disorders encephalopathy hypertension indications leukemia lymphocytic mds myelodysplasia myelodysplastic person
Pancytopenia - Workup and Differential Diagnosis Algorithm Consumption Disorders 1. Autoimmune Mediated Pancytopenia 2. Splenic Sequestration Peripheral Destruction
Pancytopenia - Workup ... HLH syndrome 5. ... FISH • Acquired Aplastic ... marrow failure syndrome ... #Workup #Differential
Pancytopenia - Workup and Differential Diagnosis Algorithm Consumption Disorders 1. Autoimmune Mediated Pancytopenia 2. Splenic Sequestration Peripheral Destruction
Pancytopenia - Workup ... HLH syndrome 5 ... FISH • Acquired Aplastic ... marrow failure syndrome ... #Workup #Differential
Aplastic Anemia - Overview Who? • M = F • 3 peaks: 1) Childhood 2) 15-25 years 3) >60 years What? • Aplastic anemia
= Hypocellular bone ... marrow + pancytopenia ... - Antithyroid medications ... • Peripheral Pancytopenia ... anemia Treatment
Myelodysplastic Syndromes (MDS) What? Myelodysplastic syndromes are a group of disorders caused by blood cells that are poorly
formed or don’t work ... Causes • Anemia • Aplastic ... factor (GCSF) treatments ... Workup: • Complete ... marrow studies Treatment
Causes of Thrombocytopenia and Platelet Disorders - Differential Diagnosis and Workup History: - Prior platelet count, family
Diagnosis and Workup ... family history - Medications ... (CVID, WAS), (neurologic ... candidate) - Bone ... ITP, unexplained pancytopenia
Chronic Lymphocytic Leukemia - Summary Cancer affecting lymphocytes/Mature B cell neoplasm • Lymphocytes accumulate in large numbers
Pure red cell aplasia ... microglobulin Treatment ... Warm AIHA • Bone ... • Richter’s Syndrome ... Leukemia #diagnosis #workup
Posterior Reversible Encephalopathy Syndrome (PRES) Overview Clinico-Radiological Syndrome, characterized by: • Headache • Seizures • Altered mental
may precede the neurologic ... Transplantation including bone ... Electrolyte abnormality, Medication ... epilepticus Treatment ... underlying cause • Treatment
Causes of Secondary Hypertension - Workup and Differential Diagnosis Approach (when evaluation should be done): 1. Severe or
Hypertension - Workup ... evaluation should be done ... heart failure, neurologic ... Neurologic disorders ... #Hypertension #Workup
Stiff Person Syndrome (SPS) - Diagnosis and Management Summary Epidemiology: • Prevalence: 1-2 cases per million -
autoimmune response gone ... antibody that works ... Treatment: • ... Diagnosis #Management #treatment ... #neurology
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