13 results
Hemolysis - Diagnostic Algorithm and Causes

Increased red cell production: 
 • Increased Reticulocytosis/polychromasia 
 • Erythroid
Hemolysis - Diagnostic ... hyperplasia of bone ... Causes #Workup #Hematology ... #Diagnosis * ... GrepMed Recommended Text
SAPHO Syndrome Summary

What?
SAPHO syndrome is a rare chronic inflammatory disorder of bone, joint, and skin characterized
inflammatory disorder of bone ... swelling of the bone ... • Bone and joint ... as the collar bone ... SAPHO #Syndrome #Rheumatology
Causes of Thrombocytopenia and Platelet Disorders - Differential Diagnosis and Workup
History:
 - Prior platelet count, family
- Differential Diagnosis ... K), H. pylori test ... thyroid function test ... candidate) - Bone ... Causes #Workup #hematology
Macrophage Activation Syndrome (MAS)
Classified among the secondary or acquired forms of haemophagocytic lymphohistiocytosis (sHLH)

What?
A subset of
hemophagocytosis in the bone ... CD163 staining of bone ... is found in the bone ... #Management #Hematology ... #Rheumatology
Cold Urticaria
Prevalence - 0.05% in the population
Disease onset - Mostly 2nd to 4th decades of life
Causes
resolve within one ... Disorientation, vertigo Diagnostic ... test, TempTest ... Cold #Urticaria #diagnosis ... #rheumatology #
Approach to Joint Pain

History:
Is the pain from:
	• Joint
	• Adjacent bursa
	• Tendon
	• Ligament
	• Bone
	• Muscle
	• Referred from
• Ligament • Bone ... present both at rest ... the subchondral bone ... Joint #Pain #MSK #rheumatology ... #differential #diagnosis
Oncologic Emergencies - Differential Diagnosis Framework

HEMATOLOGIC ONCOLOGIC EMERGENCIES:
Hyperviscosity Syndrome:
 • Spontaneous bleeding
 • Shortness of breath
- Differential Diagnosis ... Framework HEMATOLOGIC ... sustained over a one-hour ... • Dyspnea at rest ... shoulder pain, collateral
Chronic Lymphocytic Leukemia - Summary

Cancer affecting lymphocytes/Mature B cell neoplasm
 • Lymphocytes accumulate in large numbers
adults in the west ... phenomenon CLL Diagnosis ... Warm AIHA • Bone ... lymphoma • Marginal zone ... workup #oncology #hematology
Polycythemia - Differential Diagnosis Algorithm
Polycythemia itself isn’t a diagnosis. Like many things, it is a condition
Remember that a one-off ... check at least one ... Better call hematology ... Best to have an ... Algorithm #workup #hematology
Giant cell arteritis (GCA)

Giant cell arteritis (GCA) definition: Most common systemic inflammatory vasculitis in older adults
Diagnosis = clinical ... present variably: On one ... the “Chewing gum test ... positive at least one ... them, but urgent rheumatology