11 results
Causes of Bone/Joint Pain in Sickle Cell Disease
Vaso-occlusive pain:
 • Mechanism: ischemic pain
 • Can present
Causes of Bone/Joint ... in Sickle Cell Disease ... predispose to other orthopedic ... #differential # ... #hematology
Vascular Joint Pain - Differential Diagnosis Algorithm 
 - Constant Pain (Ischemia)
 - Acute Onset
 -
• Sickle Cell Anemia ... Peripheral Vascular Disease ... fractured long bone ... Diagnosis #Algorithm #Orthopedics ... #Causes
Causes of Thrombocytopenia and Platelet Disorders - Differential Diagnosis and Workup
History:
 - Prior platelet count, family
Platelet Disorders - Differential ... PT, aPTT(liver disease ... changes), high MCV anemia ... candidate) - Bone ... #Workup #hematology
Purpura - Differential Diagnosis Framework

Non-blanchable, dark red to purple, hemorrhagic skin lesions that result from leakage
Purpura - Differential ... Drug induced - Bone ... - Hemolytic anemia ... Vasculopathy #Purpura #Differential ... #nonpalpable #dermatology
Vibrio Vulnificus skin infection
Cirrhosis w/recent consumption of raw oysters w/rapidly evolving rash. 
Vibrio vulnificus part of
months temperate zones ... chronic liver disease ... hemochromatosis, hemolytic anemia ... rash #cellulitis #dermatology ... #legs #clinical
Clinical Classification of Pulmonary Hypertension

1. Pulmonary arterial hypertension from pulmonary vasculopathy
Idiopathic pulmonary arterial hypertension
Heritable gene mutations
Clinical Classification ... mutations - BMPR2 (bone ... Chronic hemolytic anemia ... Classification #Diagnosis #Differential ... #Causes
Myelodysplastic Syndromes (MDS)

What?
Myelodysplastic syndromes are a group of disorders caused by blood cells that are poorly
Out Secondary Causes ... AnemiaBone ... Myeloproliferative Disease ... blood count with differential ... Syndromes #diagnosis #hematology
Hodgkin's Lymphoma Overview

Hodgkin's lymphoma (HL) is an uncommon hematological malignancy arising from mature B cells. It
Hodgkin Lymphoma - Clinical ... Weight loss • Anemia ... Immunohistochemical studies (to differentiate ... anymore • Routine bone ... number of sites of disease
Anemia of Hospitalization - Pathophysiology

Why does the Hgb/Hct drop in the first two days during hospitalization?

Interestingly,
loss of muscle, bone ... the Journal of Clinical ... reasoning during clinical ... of renal disease ... pathophysiology #differential
Nontuberculous Mycobacteria (NTM) Infections 

Mycobacterial species other than those belonging to the Mycobacterium tuberculosis complex and
status NTM Cause ... ) - Bone Marrow ... - Anemia, neutropenia ... : • Clinical ( ... NTM #Infections #differential