24 results
Patterns of Diseases on MRI FLAIR - Differential Diagnosis
ADEM, Adreno-leukodystrophy, CADASIL, CNS, Lymphoma, High-Grade Glioma, HIV
on MRI FLAIR - ... Differential Diagnosis ... CADASIL, CNS, Lymphoma ... #MRI #Differential ... neuroradiology #clinical
Monoclonal Gammopathy of Clinical Significance (MGUS) - Differential Diagnosis

Neurologic-Centered:
 (+) Systemic Features: POEMS, AL amyloid, Cryoglobulinemia
Gammopathy of Clinical ... Significance (MGUS ... ) - Differential ... Ig deposition disease ... Diagnosis #hematology
Causes of Bone/Joint Pain in Sickle Cell Disease
Vaso-occlusive pain:
 • Mechanism: ischemic pain
 • Can present
in Sickle Cell Disease ... • XR, MRI to ... • Differentiate ... #differential # ... diagnosis #causes #hematology
Paraproteinemias

Entities That Can Feature A Monoclonal Protein/M Component:
• MM
• WM
• MGUS
• MGCS
• MGRS
• Splenic Marginal Zone
Marginal Zone Lymphoma ... • Heavy Chain disease ... Marginal zone lymphoma ... Sneddon-Wilkinson disease ... #Monoclonal #Differential
Hodgkin's Lymphoma vs Non-Hodgkin's Lymphoma - Comparison

Hodgkin's Lymphoma:
 • Epidemiology: young adults 20-30, older 50-70
 •
Clinical features ... Noncontiguous spread • Clinical ... involvement Differential ... oncology #diagnosis #differential ... #hematology
Multiple Myeloma and Monoclonal Gammopathies
C - HyperCalcemia- calcium > 11 mg/dL / >1 mg/dL the ULN
R
ULN R - Renal disease ... more: • Clonal bone ... focal lesions on MRI ... #Gammopathies #MGUS ... #diagnosis #hematology
B-Cell Acute Lymphoblastic Leukemia/Lymphoblastic Lymphoma
Clinical
 - Primarily a disease of childhood, 75% <6 yo
 - Increased
/Lymphoblastic Lymphoma ... Clinical - Primarily ... a disease of childhood ... , soft tissue, bone ... CNS involvement, MRD
Hodgkin's Lymphoma Overview

Hodgkin's lymphoma (HL) is an uncommon hematological malignancy arising from mature B cells. It
- Clinical Presentation ... Immunohistochemical studies (to differentiate ... anymore • Routine bone ... number of sites of disease ... classification #hematology
Hemophagocytic Lymphohistiocytosis (HLH)
Pathophysiology: Triggering factor (infection,...)→Activation of CD8 T cells (IFN-y) → Excessive activation of macrophages
accumulation of clinical ... , Biological + Bone ... /ml, ↑ LDH • Bone ... , B-cell lymphoma ... treatment #summary #rheumatology
Cold Agglutinin Disease

3 Types of Cold Sensitive Antibodies:
  1. Cold Agglutinins (CAD)
  2. Donath-Landsteiner
autoimmune disorder or lymphoid ... - Monoclonal - Lymphoid ... Viral Infection Clinical ... younger pts) Differential ... significance (MGUS