11 results
Clinical Classification of Pulmonary Hypertension

1. Pulmonary arterial hypertension from pulmonary vasculopathy
Idiopathic pulmonary arterial hypertension
Heritable gene mutations
Clinical Classification ... mutations - BMPR2 (bone ... pulmonary disease ... multifactorial mechanisms Hematologic ... Hypertension #PHTN #Classification
Macrophage Activation Syndrome (MAS)
Classified among the secondary or acquired forms of haemophagocytic lymphohistiocytosis (sHLH)

What?
A subset of
A subset of hemophagocytic ... CD163 staining of bone ... is found in the bone ... Syndrome #Diagnosis #Management ... #Hematology #Rheumatology
Hemophagocytic Lymphohistiocytosis (HLH)
Definition: Overwhelming clinical syndrome associated with excessive macrophage activation and cytokine storm due to
Hemophagocytic Lymphohistiocytosis ... age, however the disease ... Hemophagocytosis in bone ... Lymphohistiocytosis #diagnosis #management ... #treatment #hematology
Hemophagocytic Lymphohistiocytosis (HLH)
Pathophysiology: Triggering factor (infection,...)→Activation of CD8 T cells (IFN-y) → Excessive activation of macrophages
Hemophagocytic Lymphohistiocytosis ... , Biological + Bone ... /ml, ↑ LDH • Bone ... • Autoimmune diseases ... Lymphohistiocytosis #diagnosis #management
SAPHO Syndrome Summary

What?
SAPHO syndrome is a rare chronic inflammatory disorder of bone, joint, and skin characterized
inflammatory disorder of bone ... osteoarticular and skin disease ... SAPHO #Syndrome #Rheumatology ... #diagnosis #management ... #Dermatology
Hemophagocytic Lymphohistiocytosis (HLH) Treatment
Primary HLH:
 - HLH-94 Protocol
    • Dexamethasone
Hemophagocytic Lymphohistiocytosis ... or autoimmune disease ... for refractory disease ... HLH #Treatment #management ... #hematology
Nontuberculous Mycobacteria (NTM) Infections 

Mycobacterial species other than those belonging to the Mycobacterium tuberculosis complex and
Illnesses: • Pulmonary ... Growers (Runyon Classification ... Growers (Runyon Classification ... Hematologic malignancy ... ) - Bone Marrow
Polycythemia Vera (PV) - Diagnosis and Management Summary
Diagnostic Criteria:
 • Elevated hemoglobin and/or hematocrit AND
 •
Diagnosis and Management ... Hypercellular bone ... von Willebrand disease ... PV #Diagnosis #Management ... Summary #treatment #hematology
Hodgkin's Lymphoma Overview

Hodgkin's lymphoma (HL) is an uncommon hematological malignancy arising from mature B cells. It
-95% of cases) Classification ... anymore • Routine bone ... number of sites of disease ... #hematology #oncology ... #management
A quick infographic on various pearls about atopic dermatitis, a disease with an increasing burden on
risk factors, management ... #management #medications ... dermatitis #eczema #dermatology ... Chinellato I, Boner ... corticosteroids in dermatology