38 results
Primary and Secondary Causes of Osteoporosis

Primary osteoporosis 
 - idiopathic juvenile osteoporosis 
 -  postmenopausal
Causes of Osteoporosis ... Secondary osteoporosis ... intolerance Bone ... #Secondary #Causes ... Differential #Endocrine #Diagnosis
Purpura - Differential Diagnosis Framework

Non-blanchable, dark red to purple, hemorrhagic skin lesions that result from leakage
- Differential Diagnosis ... leakage of RBC's secondary ... induced - Bone ... Kasabach-Merritt syndrome ... #hematology #rheumatology
Priapism 

Secondary Causes:
Medications- intracavernosal injections, anticoagulants, PDE5 inhibitors, alpha blockers, methylphenidate, cocaine
Any hyperviscosity syndrome (SCD, leukemia,
Priapism Secondary ... Causes: Medications ... hyperviscosity syndrome ... #Priapism #Diagnosis ... #Management #Urology
Myelodysplastic Syndrome (MD) - Diagnosis and Management Summary
myelo (marrow) -dys- (abnormal) -plastic (shape) = funny-shaped cells
Myelodysplastic Syndrome ... old, ~10,000 new cases ... • Bone marrow ... Myelodysplastic #Syndrome ... #hematology #oncology
Low Alkaline Phosphatase - Hypophosphatasia 

Is Low Alkaline Phosphatase Of Clinical Importance?

ALP enzyme- Discovered in 1923
Low
Most cases diagnosed ... pain • loss of secondary ... mineralization Symptoms ... Phosphatase: • Other causes ... Hyophosphatasia #hepatology
SAPHO Syndrome Summary

What?
SAPHO syndrome is a rare chronic inflammatory disorder of bone, joint, and skin characterized
• A clinical diagnosis ... Rule out other causes ... #Rheumatology # ... diagnosis #management ... #Dermatology
Adrenal Insufficiency - Diagnosis and Management Summary
Primary Adrenal Insufficiency:
Most Common Cause in the US: Autoimmune Adrenalitis
Other
and Management ... ketoconazole, etomidate) Symptoms ... Causes of Secondary ... hypophysitis, Sheehan's syndrome ... #Diagnosis #Management
Irritable Bowel Syndrome (IBS) - Diagnosis and Management Summary
Diagnosis:
 • Use a positive diagnostic strategy with
Irritable Bowel Syndrome ... and Management ... Rifaximin- up to 3 courses ... Irritable #Bowel #Syndrome ... #Diagnosis #Management
Abnormal liver function tests algorithm.
 This figure details the initial response to abnormal liver blood tests.
suspicious clinical symptoms ... urgent referral to secondary ... presence of metabolic syndrome ... or referral to secondary ... Abnormal #Algorithm #Hepatology
Macrophage Activation Syndrome (MAS)
Classified among the secondary or acquired forms of haemophagocytic lymphohistiocytosis (sHLH)

What?
A subset of
Classified among the secondary ... CD163 staining of bone ... is found in the bone ... #Diagnosis #Management ... #Hematology #Rheumatology