17 results
Causes of Thrombocytopenia and Platelet Disorders - Differential Diagnosis and Workup
History:
 - Prior platelet count, family
- Differential ... pylori test (GI symptoms ... candidate) - Bone ... not required in all ... #Differential #
Alkaline Phosphatase (ALP) Elevation - Differential Diagnosis Algorithm

ALP:
 - Enzymes that catalyze hydrolysis of organic phosphate
) Elevation - Differential ... • Liver (80%) ... Intestine - Other causes ... Most common symptoms ... symptoms - Pain
Abnormal liver function tests algorithm.
 This figure details the initial response to abnormal liver blood tests.
/or suspicious clinical ... symptoms/signs ... ALP, alkaline phosphatase ... Abnormal #Algorithm #Hepatology ... #Differential #
Low Alkaline Phosphatase - Hypophosphatasia 

Is Low Alkaline Phosphatase Of Clinical Importance?

ALP enzyme- Discovered in 1923
Low
Phosphatase Of Clinical ... synthesized in: liver ... mineralization Symptoms ... Phosphatase: • Other causes ... Hyophosphatasia #hepatology
Syphilitic gummas in Tertiary syphilis
Tertiary syphilitic gummas may mimic basal cell carcinoma. The gummatous tumors are
though there are no signs ... or symptoms. ... blood vessels, liver ... , bones, and joints ... #photo
Acute Fatty Liver of Pregnancy (AFLP)
Pathophysiology:
 • Defect in fetal free fatty acid metabolism products →
postpartum): • Initial symptoms ... = nonspecific (nausea ... infiltration) Differential ... Maternal Support - Critical ... Pregnancy #hepatology
Post-Transplantation Lymphoproliferative Disorders (PTLD)
Definition: Lymphoid and/or plasmacytic proliferations that occur as a result of immunosuppression in
Lymphoproliferative Disorders ... accounts for 21% of all ... in lung>heart>liver ... , unexplained hematologic ... to 50% of PTLD cases
Fever of Unknown Origin (FUO) - Further Workup

 • CNS symptoms? Get an LP and imaging
Workup • CNS symptoms ... thin smear • Signs ... node biopsy • Clinical ... values supporting hematologic ... Bone marrow biopsy
Primary Biliary Cirrhosis (PBC) - Summary

PBC Epidemiology:
 • Female:Male 9:1
 • Common European descent
 • Age:
intralobular bile ducts causes ... failure PBC Signs ... and Symptoms: ... obstruction • ALP ... bile ducts Differential
Vibrio Vulnificus skin infection
Cirrhosis w/recent consumption of raw oysters w/rapidly evolving rash. 
Vibrio vulnificus part of
months temperate zones ... All oysters at Chesapeake ... sepsis: chronic liver ... #legs #clinical ... #photo