13 results
Hodgkin's Lymphoma vs Non-Hodgkin's Lymphoma - Comparison

Hodgkin's Lymphoma:
 • Epidemiology: young adults 20-30, older 50-70
 •
- B symptoms ... involvement Differential ... Malignancies (eg CML, ALL ... oncology #diagnosis #differential ... #hematology
Liver Chemistry Tests - AST, ALT, Alkaline Phosphatase and Bilirubin Metabolism
AST and ALT:
 • AST: liver
Liver Chemistry ... Other locations: bone ... HershShroff #Liver #Chemistry ... AlkPhos #Bilirubin #Hepatology ... #Pathophysiology
Hodgkin's Lymphoma Overview

Hodgkin's lymphoma (HL) is an uncommon hematological malignancy arising from mature B cells. It
accounts for 10% of all ... ingestion • B symptoms ... Immunohistochemical studies (to differentiate ... anymore • Routine bone ... classification #hematology
Liver Chemistries - Interpretation of LFTs

R-value: Serum (ALT/ULN ALT) / (Alk phos/ULN ALP)
 • R >
Cholestasis • ALP ... : Bone, First trimester ... Hemolysis #liver #chemistry ... #diagnosis #differential ... #Hepatology #transaminitis
Alkaline Phosphatase (ALP) Elevation - Differential Diagnosis Algorithm

ALP:
 - Enzymes that catalyze hydrolysis of organic phosphate
) Elevation - Differential ... Most common symptoms ... symptoms - Pain ... #Elevation #Differential ... Diagnosis #Algorithm #hepatology
Low Alkaline Phosphatase - Hypophosphatasia 

Is Low Alkaline Phosphatase Of Clinical Importance?

ALP enzyme- Discovered in 1923
Low
• softening of bones ... of feet, thigh bones ... collection with EDTA Pathophysiology ... mineralization Symptoms ... Hyophosphatasia #hepatology
Lymphomas and Lymphoproliferative Disorders - Differential Diagnosis Algorithm
Hodgkin Lymphoma ~40% - Characteristic For Reed-Sternberg (RS) Cells
Diagnosis Algorithm Hodgkin ... lymphocyte predominant (LP ... Depletion Non-Hodgkin ... pattern of spread, B symptoms ... Classification #pathophysiology
Acute Fatty Liver of Pregnancy (AFLP)
Pathophysiology:
 • Defect in fetal free fatty acid metabolism products →
) Pathophysiology ... postpartum): • Initial symptoms ... infiltration) Differential ... Liver #Pregnancy #hepatology ... diagnosis #management #pathophysiology
Abnormal liver function tests algorithm.
 This figure details the initial response to abnormal liver blood tests.
suspicious clinical symptoms ... box indicates all ... ALP, alkaline phosphatase ... Abnormal #Algorithm #Hepatology ... Liver #Enzymes #Differential
Primary Biliary Cirrhosis (PBC) - Summary

PBC Epidemiology:
 • Female:Male 9:1
 • Common European descent
 • Age:
65 years PBC Pathophysiology ... PBC Signs and Symptoms ... obstruction • ALP ... bile ducts Differential ... diagnosis #workup #hepatology