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diagnosis endocrinology management cardiology gh growthhormone pediatrics anomalous atrioventricular defect endocardial excess feedbackloop overproduction pituitary pulmonary return septal summary symptoms
Atrioventricular Septal Defect aka AV canal defect aka endocardial cushion defect • Epidemiology and Associations • Embryology
aka endocardial cushion ... Physical Exam • Pathophysiology ... Outcomes by Cara ... #endocardial #cushion ... diagnosis #management #peds
Growth Hormone Excess - Pathogenesis and clinical findings • Acromegaly and gigantism share the same pathophysiology
share the same pathophysiology ... -> acromegaly ... overgrowth: • Carpal ... Overproduction #diagnosis #signs ... endocrinology #pathophysiology
Acromegaly - Diagnosis and Management Summary - GrepMed Handbook Clinical Presentation: • Classic Acromegaly: frontal
paresthesias (carpal ... decade → peripheral/acral ... before epiphyseal fusion ... malignancy Pathophysiology ... Endocrinology #Treatment #Pathophysiology
Feedback Loop: Growth Hormone (GH) Growth Hormone: • Liver -> GHR activates JAK-STAT pathway -> Incr IGF1
activates lipolysis Signs ... - Giantism or acromegaly ... expansion (e.g. carpal ... endocrinology #pathophysiology
Total Anomalous Pulmonary Venous Return (TAPVR) • Introduction • Classification • Pathophysiology of TAPVR • Presentation
Classification • Pathophysiology ... Classic “snowman sign ... Outcomes by Cara ... management #cardiology #peds
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