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diagnosis management hematology mds myelodysplastic aplastic arteritis cardiotoxicity checkpoint classification common complexes cvid differential gca giantcell hodgkins hypogammaglobulinemia ici immunodeficiency
Myelodysplastic Syndrome (MD) - Diagnosis and Management Summary myelo (marrow) -dys- (abnormal) -plastic (shape) = funny-shaped cells
marrow) -dys- (abnormal ... old, ~10,000 new cases ... cytopenias (usually anemia ... only curative treatment ... #hematology #oncology
Aplastic Anemia - Overview Who? • M = F • 3 peaks: 1) Childhood 2) 15-25 years 3) >60 years What? • Aplastic anemia
and petechiae Causes ... syndrome (MDS) (normal ... megakaryocytes and a normal ... Treatment: ... #oncology #hematology
Myelodysplastic Syndromes (MDS) What? Myelodysplastic syndromes are a group of disorders caused by blood cells that are poorly
group of disorders caused ... skin that are caused ... (petechiae) • Frequent ... Syndromes #diagnosis #hematology ... #oncology
Hodgkin's Lymphoma Overview Hodgkin's lymphoma (HL) is an uncommon hematological malignancy arising from mature B cells. It
Weight loss • Anemia ... Immune hemolytic anemia ... products that define normal ... Hodgkin Lymphoma Treatment ... #oncology #management
Common Variable Immunodeficiency (CVID) What? CVID: Immunodeficiency disorder with hypogammaglobulinemia -> increased infection risk secondary to impaired B-cell
microorganisms or who have frequent ... autoimmune hemolytic anemia ... levels are within normal ... DDX - Other causes ... hypogammaglobulinemia #immunology #hematology
Giant cell arteritis (GCA) Giant cell arteritis (GCA) definition: Most common systemic inflammatory vasculitis in older adults
complications frequently ... 50 in GCA, but normal ... systemic complaints- anemia ... Treatment of GCA ... them, but urgent rheumatology
Premature Ventricular Complexes (PVC's) - Summary Framework Why PVCs? Can be the first manifestation of cardiac
heart disease Causes ... (≥ 0.12s) with abnormal ... may result from frequent ... more intensive treatment ... #differential #cardiology
Management of Immune Checkpoint Inhibitor (ICI) Induced Cardiotoxicity Problem - Immune checkpoint inhibitors (ICIs) are associated with
suggestion for frequency ... other potential causes ... Cardiotoxicity #cardiology ... #oncology #management ... #treatment
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