12 results
Differentiation Syndrome in APML
Epidemiology:
 • Incidence: common in APL (2-48% depending on the study)
 • Triggers:
Differentiation Syndrome ... in APML Epidemiology ... PE, DAH, CHF, Anaphylaxis ... organ dysfuxtion, ICU ... #management #hematology
Tumor Lysis Syndrome - Workup and Management

Initial workup: BMP, Serum uric acid, LDH, Urine output, Consider
Tumor Lysis Syndrome ... - Workup and Management ... Initial workup ... abnormalities • Cardiac ... monitoring • Consider ICU
Peri-operative Hyperthermia - Guidelines for Crises in Anaesthesia
If prolonged or ≥ 39 C this is a
Allergic reaction / anaphylaxis ... • Serotonin syndrome ... Anesthesiology #Anesthesia #Checklist ... #Diagnosis #Management ... #Workup
Intraoperative Anaphylaxis - Guidelines for Crises in Anaesthesia
• Unexplained hypotension
• Unexplained bronchospasm (wheeze may be absent
Intraoperative Anaphylaxis ... • Unexpected cardiac ... Intraoperative #Checklist ... #Diagnosis #Management ... #Workup
Cardiac Arrest - Guidelines for Crises in Anaesthesia

The probable cause is one or more of: something
reservoir bag and APL ... 10) Acidosis Anaphylaxis ... CardiacArrest #Checklist ... #Diagnosis #Management ... #Workup
Hypotension - Guidelines for Crises in Anaesthesia

Hypotension is commonly due to unnecessarily deep anaesthesia, the autonomic
reservoir bag and APL ... ischaemia → 3-12 o Anaphylaxis ... Intraoperative #Checklist ... #Diagnosis #Management ... #Workup
Can’t Intubate, Can’t Oxygenate (CICO) - Guidelines for Crises in Anaesthesia
This is the last resort when
optimal airway management ... ENT, ICU). ❹ Call ... trolley and then cardiac ... Intraoperative #Checklist ... #Workup
Intraoperative Tachycardia - Guidelines for Crises in Anaesthesia
Tachycardia in theatre is often due to inadequate depth
hypovolaemia; primary cardiac ... amniotic (→ 3-5); anaphylaxis ... Intraoperative #Checklist ... #Diagnosis #Management ... #Workup
Increased Airway Pressure - Guidelines for Crises in Anaesthesia

Using these steps from start to end should
reservoir bag and APL ... Bronchospasm → 3-4 o Anaphylaxis ... Intraoperative #Checklist ... #Diagnosis #Management ... #Workup
Intraoperative Hypertension - Guidelines for Crises in Anaesthesia
Hypertension is most commonly due to inappropriate depth of
reservoir bag and APL ... overload / TURP syndrome ... Intraoperative #Checklist ... #Diagnosis #Management ... #Workup