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diagnosis hematology management amyloid amyloidosis clinical dermatology differential encephalopathy gammopathies hearing knee leukemia loss mds mgus monoclonal msk multiplemyeloma myelodysplasia
Multiple Myeloma and Monoclonal Gammopathies C - HyperCalcemia- calcium > 11 mg/dL / >1 mg/dL the ULN R
g/dl LLN B - Bony ... more: • Clonal bone ... focal lesions on MRI ... plasmacytoma, POEMs syndrome ... diagnosis #hematology #oncology
Osgood-Schlatter Disease - MSK Radiology Imaging Findings: • Infrapatellar fat-pad edema with loss of the patellar tendon
fragmentation and mild bone ... possible secondary ossification ... • MRI is more sensitive ... marrow edema and bony ... patella #clinical #mri
SAPHO Syndrome Summary What? SAPHO syndrome is a rare chronic inflammatory disorder of bone, joint, and skin characterized
inflammatory disorder of bone ... • Bone and joint ... Rule out other causes ... - MRI: inflammation ... osteoarticular and skin disease
Myelodysplastic Syndromes (MDS) What? Myelodysplastic syndromes are a group of disorders caused by blood cells that are poorly
hypercellular bone ... megakaryocytic Bone ... Aplastic Anemia • Bone ... the blood and bone ... blood smear • Bone
Leukemias Overview: ALL, CML, AML, APML, CLL Acute leukemias > 20% blasts in the peripheral blood smear
blood smear or on bone ... bleeding, infections, bone ... cells - Blood and Bone ... • Headaches, bone ... neutropenia) • Bone
Hearing Loss - Differential Diagnosis Framework Hearing Loss Types: • Conductive • Sensorineural • Mixed Presbycusis is the most common type
Normal: Air > bone ... hearing loss: Bone ... Onset ○ Meniere disease ... II ○ Susac’s syndrome ... ○ HIV ○ Lyme disease
Posterior Reversible Encephalopathy Syndrome (PRES) Overview Clinico-Radiological Syndrome, characterized by: • Headache • Seizures • Altered mental
Shock, Autoimmune disease ... Transplantation including bone ... Vascular narrowing on MRA ... the underlying cause ... with AEDs until cause
Amyloidosis - Summary Group of disorders associated with extracellular deposition of fibrils formed from low-molecular-weight proteins in
the extent of disease ... : • Nephrotic syndrome ... muscle wasting Bone ... Carpal tunnel syndrome ... enlargement • MRI
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