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diagnosis b12 cobalamin disorders erythematosus feedbackloop gh growthhormone hematology ketones ketosis lupus mds myelitis myelodysplasia myelodysplastic neurology nutrition oncology pituitary
Ketosis Disorders Ketone bodies are a normal metabolic energy source. Excessive unregulated production of ketones, often accompanied
complete insulin deficiency ... partial insulin deficiency ... Disorders #ketones #differential ... #diagnosis #management ... #endocrinology
Feedback Loop: Growth Hormone (GH) Growth Hormone: • Liver -> GHR activates JAK-STAT pathway -> Incr IGF1
lipolysis Signs/Symptoms ... : • GH deficiency ... : - Short ... #FeedbackLoop #endocrinology ... #pathophysiology
Vitamin B12 (Cobalamin) Deficiency Etiology: • Vit B12 - aka cobalamin. Present in foods derived from animal
B12 (Cobalamin) Deficiency ... : • Vit B12 - aka ... to manifest its symptoms ... , alcohol use, symptoms ... #diagnosis #management
Myelodysplastic Syndromes (MDS) What? Myelodysplastic syndromes are a group of disorders caused by blood cells that are poorly
age 70 years Symptoms ... Pinpoint-sized red spots ... or folic acid deficiency ... treatments • Copper deficiency ... blood count with differential
Transverse Myelitis Overview Focal inflammatory disorder of the spinal cord resulting in rapid onset of weakness, sensory
monophasic Pathophysiology ... Bilateral signs and/or symptoms ... • Nutritional Deficiency ... Myelitis #diagnosis #management ... #neurology #differential
SLE (Systemic Lupus Erythematosus) Suspect: Clinical evidence of (fatigue, rash, photosensitivity, inflammatory arthritis, weight loss, and fever) and
permanent alopecia Differential ... disease • Prolidase deficiency ... • Malar rash - spares ... Induced Lupus: • Symptoms ... and C4) • ds-DNA
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