11 results
Hemophagocytic Lymphohistiocytosis (HLH)
Pathophysiology: Triggering factor (infection,...)→Activation of CD8 T cells (IFN-y) → Excessive activation of macrophages
Lymphohistiocytosis (HLH) Pathophysiology ... , Biological + Bone ... /ml, ↑ LDH • Bone ... • Autoimmune diseases ... #summary #rheumatology
Macrophage Activation Syndrome (MAS)
Classified among the secondary or acquired forms of haemophagocytic lymphohistiocytosis (sHLH)

What?
A subset of
juvenile idiopathic arthritis ... juvenile idiopathic arthritis ... SLE], AOSD) • Infection ... Treatment: • Corticosteroids ... #Rheumatology
SAPHO Syndrome Summary

What?
SAPHO syndrome is a rare chronic inflammatory disorder of bone, joint, and skin characterized
nonerosive inflammatory arthritis ... causes such as infectious ... and lower jaw Treatment ... osteoarticular and skin disease ... SAPHO #Syndrome #Rheumatology
Mycoses

HISTOPLASMOSIS
• Inhalation of conidia → Yeast → travel to lymph nodes → spread in body
• Bird
pulmonary symptoms • Rheumatologic ... extrapulmonary disease ... or meningitic disease ... Aspergillosis Pathophysiology ... Meningitis, septic arthritis
Giant cell arteritis (GCA)

Giant cell arteritis (GCA) definition: Most common systemic inflammatory vasculitis in older adults
with systemic, neurologic ... vasculitis vs infection ... of the steroid treatment ... Treatment of GCA ... them, but urgent rheumatology
IDSA Recommendations for Treating Coccidiodomycosis in HIV-AIDS
Treating Mild Infections (Such As Focal Pneumonia or asymptomatic patients
IDSA Recommendations ... with positive serology ... BII)* Treating Bone ... Extrathoracic Disseminated Disease ... #Prevention #Treatment
Posterior Reversible Encephalopathy Syndrome (PRES) Overview

Clinico-Radiological Syndrome, characterized by:
 • Headache
 • Seizures
 • Altered mental
may precede the neurologic ... Shock, Autoimmune disease ... Etiology: • Pathophysiology ... Diagnosis: • Infection ... epilepticus Treatment
The Stages of Syphilis 

Primary Syphilis 
- The chancre lesion is the hallmark of primary syphilis.
Without treatment ... to asymptomatic infection ... granuIomas on skin, bone ... aneurysm and coronary arteritis ... Diseases - https
Pseudogout Summary - Calcium Pyrophosphate Deposition Disease (CPPD)

Pathophysiology:
Pyrophosphate produced by chondrocytes likely precipitates with calcium to
Pyrophosphate Deposition Disease ... (CPPD) Pathophysiology ... diagnose concomitant infection ... Acute Pseudogout: Treatment ... #Rheumatology #
TAFRO

TAFRO syndrome was first described in 2010, standing for:
- Thrombocytopenia
- Anasarca
- Fever
- Reticulin fibrosis
- Organomegaly

TAFRO syndrome
fast bacterial infection ... cell lymphoma Pathophysiology ... interfollicular zone ... Hypoalbuminemia Treatment ... diagnosis #management #rheumatology