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diagnosis management lymphohistiocytosis oncology rheumatology treatment activation chronic classification cll criteria hodgkins leukemia lymphocytic lymphoma macrophage mas plasmacytoma solitary summary
Hemophagocytic Lymphohistiocytosis (HLH) Clinical Features: Fever, Splenomegaly, Hepatomegaly, Lymphadenopathy, Confusion Classic lab findings in HLH: ↑↑ ferritin, Anemia,
(HLH) Clinical ... d-dimer, ↓ NK cell ... (affecting 2 2 cell ... #Hemophagocytic ... Lymphohistiocytosis #diagnosis #hematology
Hemophagocytic Lymphohistiocytosis (HLH) Pathophysiology: Triggering factor (infection,...)→Activation of CD8 T cells (IFN-y) → Excessive activation of macrophages
Hemophagocytic Lymphohistiocytosis ... accumulation of clinical ... , Biological + Bone ... /ml, ↑ LDH • Bone ... #Hemophagocytic
Hemophagocytic Lymphohistiocytosis (HLH) Definition: Overwhelming clinical syndrome associated with excessive macrophage activation and cytokine storm due to
: Overwhelming clinical ... Low or absent NK cell ... Hemophagocytosis in bone ... #Hemophagocytic ... management #treatment #hematology
Macrophage Activation Syndrome (MAS) Classified among the secondary or acquired forms of haemophagocytic lymphohistiocytosis (sHLH) What? A subset of
A subset of hemophagocytic ... lymphohistiocytosis (HLH ... fever syndromes Clinical ... Fever is the main clinical ... hypersensitivity syndromes • HLH
Chronic Lymphocytic Leukemia - Summary Cancer affecting lymphocytes/Mature B cell neoplasm • Lymphocytes accumulate in large numbers
lymphocytes/Mature B cell ... Orange or Hep C Clinical ... Warm AIHA • Bone ... Leukemia #diagnosis #workup ... #oncology #hematology
Hodgkin's Lymphoma Overview Hodgkin's lymphoma (HL) is an uncommon hematological malignancy arising from mature B cells. It
from mature B cells ... Hodgkin Lymphoma - Clinical ... Hodgkin Lymphoma Workup ... anymore • Routine bone ... classification #hematology
Solitary Cell Plasmacytoma What? • Plasma cell neoplasms can present as a single lesion (solitary plasmacytoma) • In 3%
Solitary Cell Plasmacytoma ... • Plasma cell neoplasms ... plasmacytoma) Clinical ... Oncology #Diagnosis #Workup ... #Hematology
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