8 results
Hemophagocytic Lymphohistiocytosis (HLH)
Clinical Features: Fever, Splenomegaly, Hepatomegaly, Lymphadenopathy, Confusion
Classic lab findings in HLH: ↑↑ ferritin, Anemia,
Hemophagocytic Lymphohistiocytosis ... (HLH) Clinical ... d-dimer, ↓ NK cell ... #Hemophagocytic ... Lymphohistiocytosis #diagnosis #hematology
Hemophagocytic Lymphohistiocytosis (HLH)
Pathophysiology: Triggering factor (infection,...)→Activation of CD8 T cells (IFN-y) → Excessive activation of macrophages
Hemophagocytic Lymphohistiocytosis ... accumulation of clinical ... , Biological + Bone ... /ml, ↑ LDH • Bone ... #Hemophagocytic
Hemophagocytic Lymphohistiocytosis (HLH)
Definition: Overwhelming clinical syndrome associated with excessive macrophage activation and cytokine storm due to
: Overwhelming clinical ... Low or absent NK cell ... Hemophagocytosis in bone ... #Hemophagocytic ... management #treatment #hematology
Macrophage Activation Syndrome (MAS)
Classified among the secondary or acquired forms of haemophagocytic lymphohistiocytosis (sHLH)

What?
A subset of
A subset of hemophagocytic ... lymphohistiocytosis (HLH ... fever syndromes Clinical ... Fever is the main clinical ... Diagnosis #Management #Hematology
Chronic Lymphocytic Leukemia - Summary

Cancer affecting lymphocytes/Mature B cell neoplasm
 • Lymphocytes accumulate in large numbers
incompetent • CLL ... Orange or Hep C Clinical ... Warm AIHA • Bone ... Leukemia #diagnosis #workup ... #oncology #hematology
Hodgkin's Lymphoma Overview

Hodgkin's lymphoma (HL) is an uncommon hematological malignancy arising from mature B cells. It
accounts for 10% of all ... Hodgkin Lymphoma - Clinical ... Hodgkin Lymphoma Workup ... anymore • Routine bone ... classification #hematology
Rheumatology Workup - Laboratories Studies in Rheumatic Diseases

• Septic arthritis - Gram stain and culture of
Rheumatology Workup ... Screening Tests for All ... back pain) • HLA-B27 ... ANA and RF (if clinical ... Arthritis #laboratory #workup
Solitary Cell Plasmacytoma

What?
• Plasma cell neoplasms can present as a single lesion (solitary plasmacytoma)
• In 3%
• Plasma cell neoplasms ... MM, the plasma cell ... plasmacytoma) Clinical ... Oncology #Diagnosis #Workup ... #Hematology