13 results
Pathologic / Fragility Fractures - Differential Diagnosis Algorithm 
Tumours
 - See Bone Lesions Scheme
Paget's Disease
 -
Fragility Fractures - Differential ... Tumours - See Bone ... Marrow Disorder ... Diagnosis #Algorithm #Orthopedics ... #Causes
Alkaline Phosphatase (ALP) Elevation - Differential Diagnosis Algorithm

ALP:
 - Enzymes that catalyze hydrolysis of organic phosphate
ALP) Elevation - Differential ... - Highest • Bone ... Intestine - Other causes ... ALP #Elevation #Differential ... Diagnosis #Algorithm #hepatology
Low Alkaline Phosphatase - Hypophosphatasia 

Is Low Alkaline Phosphatase Of Clinical Importance?

ALP enzyme- Discovered in 1923
Low
Most cases diagnosed ... • softening of bones ... collection with EDTA Pathophysiology ... : • Other causes ... Hyophosphatasia #hepatology
Causes of Bone/Joint Pain in Sickle Cell Disease
Vaso-occlusive pain:
 • Mechanism: ischemic pain
 • Can present
Causes of Bone/Joint ... predispose to other orthopedic ... • Differentiate ... #diagnosis #causes ... #hematology
Causes of Thrombocytopenia and Platelet Disorders - Differential Diagnosis and Workup
History:
 - Prior platelet count, family
and Platelet Disorders ... - Differential ... candidate) - Bone ... #Differential # ... #Workup #hematology
Purpura - Differential Diagnosis Framework

Non-blanchable, dark red to purple, hemorrhagic skin lesions that result from leakage
Purpura - Differential ... , or other causes ... Drug induced - Bone ... Vasculopathy #Purpura #Differential ... #Diagnosis #hematology
Subtrochanteric Femur Fracture: Pathogenesis and clinical findings
 • Subtrochanteric region spans 5 cm distally from the
fractures in elderly Causes ... damage weakens the bone ... Fractures #msk #orthopedics ... #diagnosis #differential ... #causes #pathophysiology
Primary Biliary Cirrhosis (PBC) - Summary

PBC Epidemiology:
 • Female:Male 9:1
 • Common European descent
 • Age:
65 years PBC Pathophysiology ... intralobular bile ducts causes ... : • Alkaline phosphatase ... bile ducts Differential ... diagnosis #workup #hepatology
Acquired Disorders of Reduced Bone Strength: Pathogenesis
 • Hyperparathyroidism
 • Vitamin D deficiency
 • Malabsorption syndromes
Acquired Disorders ... of Reduced Bone ... Diabetes • Other causes ... #BoneStrength #pathophysiology ... #differential #
Myelodysplastic Syndromes (MDS)

What?
Myelodysplastic syndromes are a group of disorders caused by blood cells that are poorly
are a group of disorders ... caused by blood ... Neutropenia • Platelet Disorders ... blood count with differential ... Syndromes #diagnosis #hematology