56 results
diagnosis treatment rheumatology syndrome hepatology dermatology differential oncology summary algorithm clinical classification hemophagocytic hlh lupus lymphohistiocytosis sle alkaline alp blood
Causes of Bone/Joint Pain in Sickle Cell Disease Vaso-occlusive pain: • Mechanism: ischemic pain • Can present
Causes of Bone/Joint ... in Sickle Cell Disease ... Pain #SickleCell #Disease ... differential #diagnosis #causes ... #hematology
Alkaline Phosphatase (ALP) Elevation - Differential Diagnosis Algorithm ALP: - Enzymes that catalyze hydrolysis of organic phosphate
stimulation (placenta/Bone ... - Highest • Bone ... Intestine - Other causes ... - Bone symptoms ... Diagnosis #Algorithm #hepatology
Causes of Thrombocytopenia and Platelet Disorders - Differential Diagnosis and Workup History: - Prior platelet count, family
PT, aPTT(liver disease ... bypass), LFT (liver disease ... candidate) - Bone ... or if a primary hematologic ... #Workup #hematology
Purpura - Differential Diagnosis Framework Non-blanchable, dark red to purple, hemorrhagic skin lesions that result from leakage
Drug induced - Bone ... marrow disease ... deficiency • Liver disease ... Von Willebrand disease ... Differential #Diagnosis #hematology
Paget's Disease of Bone • Characterized by an ↑ rate of bone turnover with both excessive
Paget's Disease ... • Caused by ( ... • The disease ... medperspective #Pagets #Disease ... #management #treatment
Multiple Myeloma and Monoclonal Gammopathies C - HyperCalcemia- calcium > 11 mg/dL / >1 mg/dL the ULN R
ULN R - Renal disease ... more: • Clonal bone ... Causes of false- ... amyloidosis Other causes ... MGUS #diagnosis #hematology
Low Alkaline Phosphatase - Hypophosphatasia Is Low Alkaline Phosphatase Of Clinical Importance? ALP enzyme- Discovered in 1923 Low
Most cases diagnosed ... • softening of bones ... Malnutrition • Wilson's disease ... Phosphatase: • Other causes ... Hyophosphatasia #hepatology
SAPHO Syndrome Summary What? SAPHO syndrome is a rare chronic inflammatory disorder of bone, joint, and skin characterized
Rule out other causes ... osteoarticular and skin disease ... SAPHO #Syndrome #Rheumatology ... #diagnosis #management ... #Dermatology
Myelodysplastic Syndrome (MD) - Diagnosis and Management Summary myelo (marrow) -dys- (abnormal) -plastic (shape) = funny-shaped cells
Diagnosis and Management ... old, ~10,000 new cases ... • Bone marrow ... acute leukemia Management ... #treatment #hematology
Causes of Knee Effusions - Differential Diagnosis Framework Knee Effusion Red Flags: 1. Fever/Chills/Joint pain/Night sweats/Weight loss - DDX: -
Causes of Knee Effusions ... Effusions: - Hematologic ... - Aneurysmal bone ... Osteochondroma Hematologic ... Knee #Effusions #causes
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