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differential causes hemolytic leukemia aafp chronic classification cll folate folicacid hemolysis hodgkins homocysteine lymphadenopathy lymphocytic lymphoma macrocytosis management mds microcytic
Anemia Diagnostic Algorithm Mean corpuscular (cell) volume (MCV): Average RBC size. Under 80 = microcytic. Between 80-95
Anemia Diagnostic ... corpuscular (cell ... Red cell distribution ... #Algorithm #Diagnosis ... #Workup #Hematology
Hemolysis - Diagnostic Algorithm and Causes Increased red cell production: • Increased Reticulocytosis/polychromasia • Erythroid
Hemolysis - Diagnostic ... hyperplasia of bone ... Hemolysis #Hemolytic #Anemia ... #Causes #Workup ... #Hematology #Diagnosis
Algorithm for the evaluation of macrocytic anemia. (RBC = red blood cell; MMA = methylmalonic acid.) Physicians
Algorithm for the ... RBC = red blood cell ... is an adequate bone ... #Diagnosis #Macrocytosis ... #Macrocytic #Anemia
Causes of Diffuse Lymphadenopathy - Differential Diagnosis Algorithm Reactive: - Systemic Inflammatory •
Causes of Diffuse ... Algorithm Reactive ... Reed-Sternberg Cells ... Lymphadenopathy #LAD ... #Hematology #Oncology
Chronic Lymphocytic Leukemia - Summary Cancer affecting lymphocytes/Mature B cell neoplasm • Lymphocytes accumulate in large numbers
Diagnosis: • ... • Neutropenia, anemia ... Warm AIHA • Bone ... #workup #oncology ... #hematology
Hemolytic Anemia - Differential Diagnosis Algorithm • Sickle cells - Consider sickle cell disease (diverse genotypes):
Hemolytic Anemia ... Algorithm • Sickle ... cells - Consider ... #Algorithm #workup ... #hematology #testing
Myelodysplastic Syndromes (MDS) What? Myelodysplastic syndromes are a group of disorders caused by blood cells that are poorly
formed or don’t work ... common cytopenia: Macrocytic ... Workup: • Complete ... Myelodysplastic #Syndromes #diagnosis ... #hematology #oncology
Leukemias Overview: ALL, CML, AML, APML, CLL Acute leukemias > 20% blasts in the peripheral blood smear
blood smear or on bone ... activity • ↓ LAP ... - infiltrates (anemia ... #Leukemia #Hematology ... #Oncology #Diagnosis
Hodgkin's Lymphoma Overview Hodgkin's lymphoma (HL) is an uncommon hematological malignancy arising from mature B cells. It
Weight loss • Anemia ... Hodgkin Lymphoma Workup ... anymore • Routine bone ... classification #hematology ... #oncology #management
Solitary Cell Plasmacytoma What? • Plasma cell neoplasms can present as a single lesion (solitary plasmacytoma) • In 3%
Diagnosis? ... • No CRAB - no anemia ... #Plasmacytoma #Oncology ... #Diagnosis #Workup ... #Hematology
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