131 results
Thrombotic Microangiopathies In Systemic Lupus Erythematosus

Dr. Laurent ARNAUD @Lupusreference

#TMAs #Thrombotic #Microangiopathies #Systemic #Lupus #Erythematosus #SLE #hematology
Microangiopathies In Systemic ... Microangiopathies #Systemic ... Erythematosus #SLE #hematology ... #rheumatology # ... differential #diagnosis
Aplastic Anemia and Bone Marrow Failure Syndromes with Pancytopenia

Fanconi Anemia
Acquired Aplastic Anemia
Dyskeratosis Congenita & Telemore Biology
Aplastic Anemia and Bone ... Marrow Failure Syndromes ... Shwachman-Diamond Syndrome ... #Pancytopenia #Syndromes ... anemia #diagnosis #Hematology
Pancytopenia - Differential Algorithm / Schema

- Bone Marrow Failure
- Bone Marrow Infiltration
- Sequestration / Destruction

#Pancytopenia #Differential
Pancytopenia - Differential ... / Schema - Bone ... Marrow Failure - Bone ... #Pancytopenia #Differential ... Algorithm #Schema #Hematology
Macrophage Activation Syndrome (MAS)
Classified among the secondary or acquired forms of haemophagocytic lymphohistiocytosis (sHLH)

What?
A subset of
hemophagocytosis in the bone ... CD163 staining of bone ... is found in the bone ... Diagnosis #Management #Hematology ... #Rheumatology
ANA Patterns and Associated Rheumatic Diseases:
 • Homogeneous: Systemic lupus erythematosus (SLE), Mixed connective tissue disease
• Homogeneous: Systemic ... ) • Speckled: Systemic ... SLE), Sjogren's Syndrome ... ANA #patterns #rheumatology ... #diagnosis #differential
Diagnostic Schema for Hyperferritinemia

Pearl: Diseases associated with extreme elevations: 
1. HLH 
2. Still's disease 
3. Systemic
Systemic histoplasmosis ... Hyperferritinemia #Algorithm #Differential ... #Diagnosis #Hematology
Seronegative Inflammatory Arthritis - Differential Diagnosis
 • Seronegative Rheumatoid Arthritis 
 • Infectious Arthritis: Viral, Bacterial,
Inflammatory Arthritis - Differential ... Erythematous, Systemic ... Vasculitis, Systemic ... #arthritides #Differential ... #Diagnosis #rheumatology
Pancytopenia - Differential Diagnosis

Congenital Diseases:
• GATA2 deficiency
• Fanconi’s anemia
• Wiskott-Aldrich syndrome
• Ribosomopathy or telomeropathy

Cancer:
• Leukemia
• Lymphoma

Inflammatory
Pancytopenia - Differential ... Wiskott-Aldrich syndrome ... Autoimmune Diseases: • Systemic ... #Pancytopenia #Differential ... #Diagnosis #Hematology
Thrombocytopenia - Differential Diagnosis Algorithm

Decreased production:
 • Bone marrow suppression
 • Bone marrow failure
 • Bone
Thrombocytopenia - Differential ... production: • Bone ... suppression • Bone ... Thrombocytopenia #Differential ... Diagnosis #Algorithm #hematology
Approach to Thrombocytosis - Elevated Platelet Count - Differential Diagnosis Algorithm

Peripheral Smear concerning for malignancy?
Platelet Count - Differential ... → Refer to hematology ... Kawasaki, Nephrotic syndrome ... Thrombocytosis #Platelets #Differential ... Diagnosis #Algorithm #hematology