5 results
Alkaline Phosphatase (ALP) Elevation - Differential Diagnosis Algorithm

ALP:
 - Enzymes that catalyze hydrolysis of organic phosphate
stimulation (placenta/Bone ... - Highest • Bone ... Renal disease - Bone ... symptoms - Pain -> RUQ ... Diagnosis #Algorithm #hepatology
Low Alkaline Phosphatase - Hypophosphatasia 

Is Low Alkaline Phosphatase Of Clinical Importance?

ALP enzyme- Discovered in 1923
Low
• softening of bones ... of feet, thigh bones ... eliminated • Elevation ... &/or • Elevation ... Hyophosphatasia #hepatology
Liver Function Test (LFTs) Elevation
AST - Cardiac and skeletal muscle, kidney, brain
ALT - More specific for
Function Test (LFTs) Elevation ... abnormality vs bone ... Pattern - Alkaline Phosphatase ... FunctionTest #LFTs #Elevation ... Transaminitis #diagnosis #hepatology
Liver Chemistry Tests - AST, ALT, Alkaline Phosphatase and Bilirubin Metabolism
AST and ALT:
 • AST: liver
ALT, Alkaline Phosphatase ... liver Alkaline phosphatase ... Other locations: bone ... hepatocyte - Elevation ... AlkPhos #Bilirubin #Hepatology
Abnormal liver function tests algorithm.
 This figure details the initial response to abnormal liver blood tests.
Boxes in yellow ... magnitude of enzyme elevation ... Green boxes indicate ... ALP, alkaline phosphatase ... Abnormal #Algorithm #Hepatology