175 results
Erythroderma - Diagnostic Algorithm. Pathophysiology: 1) Extensive cutaneous capillary dilation, results in widespread exfoliation of the
Pathophysiology: ... of germinative skin ... Causes: 1) Exfoliative ... Basophils/Histamine 4) Skin-homing ... #Diagnosis #Dermatology
SAPHO Syndrome Summary

What?
SAPHO syndrome is a rare chronic inflammatory disorder of bone, joint, and skin characterized
, joint, and skin ... • Pustular skin ... dermatoses • Skin ... Rule out other causes ... SAPHO #Syndrome #Rheumatology
Causes of Bone/Joint Pain in Sickle Cell Disease
Vaso-occlusive pain:
 • Mechanism: ischemic pain
 • Can present
Causes of Bone/Joint ... Generally affects long bones ... BrighamChiefs #Bone ... differential #diagnosis #causes ... #hematology
Purpura - Differential Diagnosis Framework

Non-blanchable, dark red to purple, hemorrhagic skin lesions that result from leakage
purple, hemorrhagic skin ... • Secondary Causes ... Drug induced - Bone ... Differential #Diagnosis #hematology ... #rheumatology #
Baclofen Skin Rash

When a nursing home patient re-presents to the Emergency Department, go through their medication
Baclofen Skin Rash ... recently started ones ... #Baclofen #Skin ... #Rash #Dermatology
Causes of Thrombocytopenia and Platelet Disorders - Differential Diagnosis and Workup
History:
 - Prior platelet count, family
practices that could cause ... candidate) - Bone ... patients if the cause ... or if a primary hematologic ... #Workup #hematology
Low Alkaline Phosphatase - Hypophosphatasia 

Is Low Alkaline Phosphatase Of Clinical Importance?

ALP enzyme- Discovered in 1923
Low
Most cases diagnosed ... • softening of bones ... collection with EDTA Pathophysiology ... Phosphatase: • Other causes ... Hyophosphatasia #hepatology
Childhood Immunization Schedule: Why we immunize
 • Diphtheria Toxin -> URT inflammation causes pseudomembrane with hardened
invade URT & via hematologic ... within GI and URT causes ... CNS and hematologic ... that persists as skin ... peds #pediatrics #pathophysiology
Hemolysis - Diagnostic Algorithm and Causes

Increased red cell production: 
 • Increased Reticulocytosis/polychromasia 
 • Erythroid
Algorithm and Causes ... hyperplasia of bone ... #Differential #Causes ... #Workup #Hematology
Maculopapular - Diagnostic Algorithm
Pathophysiology:
- Catch-all term with a wide range of potential pathophysiologic mechanisms and causative
Diagnostic Algorithm Pathophysiology ... range of potential pathophysiologic ... - Pathophysiology ... sulfa-drug - Skin ... #Diagnosis #Dermatology