24 results
diagnosis management differential rheumatology syndrome dermatology hepatology treatment clinical hemophagocytic hlh knee lymphohistiocytosis radiology summary alkaline alp als amyotrophic arthritis
Causes of Bone/Joint Pain in Sickle Cell Disease Vaso-occlusive pain: • Mechanism: ischemic pain • Can present
Causes of Bone/Joint ... in Sickle Cell Disease ... • XR, MRI to ... Pain #SickleCell #Disease ... #hematology
Causes of Thrombocytopenia and Platelet Disorders - Differential Diagnosis and Workup History: - Prior platelet count, family
PT, aPTT(liver disease ... (CVID, WAS), (neurologic ... bypass), LFT (liver disease ... candidate) - Bone ... #Workup #hematology
Multiple Myeloma and Monoclonal Gammopathies C - HyperCalcemia- calcium > 11 mg/dL / >1 mg/dL the ULN R
more: • Clonal bone ... focal lesions on MRI ... Causes of false- ... amyloidosis Other causes ... MGUS #diagnosis #hematology
Osgood-Schlatter Disease - MSK Radiology Imaging Findings: • Infrapatellar fat-pad edema with loss of the patellar tendon
- MSK Radiology ... fragmentation and mild bone ... • MRI is more sensitive ... patella #clinical #mri ... Radiology #diagnosis #msk
Low Alkaline Phosphatase - Hypophosphatasia Is Low Alkaline Phosphatase Of Clinical Importance? ALP enzyme- Discovered in 1923 Low
Malnutrition • Wilson's disease ... collection with EDTA Pathophysiology ... respiratory failure • Neurologic ... Phosphatase: • Other causes ... Hyophosphatasia #hepatology
Gout (Gouty Arthritis) - MSK Radiology Imaging Findings: • Eccentric soft-tissue densities surrounding the third proximal interphalangeal
Gouty Arthritis) - MSK ... Case description ... - **MSK rads ... diffuse chondral disease ... #rheumatology
SAPHO Syndrome Summary What? SAPHO syndrome is a rare chronic inflammatory disorder of bone, joint, and skin characterized
Rule out other causes ... - MRI: inflammation ... osteoarticular and skin disease ... SAPHO #Syndrome #Rheumatology ... diagnosis #management #Dermatology
Causes of Knee Effusions - Differential Diagnosis Framework Knee Effusion Red Flags: 1. Fever/Chills/Joint pain/Night sweats/Weight loss - DDX: -
Causes of Knee Effusions ... Effusions: - Hematologic ... - Aneurysmal bone ... Knee #Effusions #causes ... differential #diagnosis #msk
Paget’s Disease: Complications Abnormal Osteoclasts cause excessive bone turnover -> Incr bone resorption, Incr (abnormal) bone formation MSK
Paget’s Disease: ... Abnormal Osteoclasts cause ... formation MSK ... causes middle ear ... PagetsDisease #pathophysiology
Hemophagocytic Lymphohistiocytosis (HLH) Pathophysiology: Triggering factor (infection,...)→Activation of CD8 T cells (IFN-y) → Excessive activation of macrophages
Lymphohistiocytosis (HLH) Pathophysiology ... , Biological + Bone ... /ml, ↑ LDH • Bone ... • Autoimmune diseases ... Adult-onset Still disease
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