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management differential rheumatology hepatology oncology causes treatment algorithm alkaline arthritis leukemia phosphatase signs summary syndrome abnormal agammaglobulinemia als amyotrophic anemia
Alkaline Phosphatase (ALP) Elevation - Differential Diagnosis Algorithm ALP: - Enzymes that catalyze hydrolysis of organic phosphate
- Differential Diagnosis ... Most common symptoms ... - Bone symptoms ... #Differential #Diagnosis ... #Algorithm #hepatology
Low Alkaline Phosphatase - Hypophosphatasia Is Low Alkaline Phosphatase Of Clinical Importance? ALP enzyme- Discovered in 1923 Low
Malnutrition • Wilson's disease ... collection with EDTA Pathophysiology ... mineralization Symptoms ... respiratory failure • Neurologic ... Hyophosphatasia #hepatology
Causes of Thrombocytopenia and Platelet Disorders - Differential Diagnosis and Workup History: - Prior platelet count, family
- Differential Diagnosis ... and Workup History ... pylori test (GI symptoms ... (CVID, WAS), (neurologic ... candidate) - Bone
Primary Biliary Cirrhosis (PBC) - Summary PBC Epidemiology: • Female:Male 9:1 • Common European descent • Age:
65 years PBC Pathophysiology ... PBC Signs and Symptoms ... but elevated as disease ... obstruction • ALP ... #workup #hepatology
Fever of Unknown Origin (FUO) - Further Workup • CNS symptoms? Get an LP and imaging
• CNS symptoms ... Get an LP and imaging ... values supporting hematologic ... Bone marrow biopsy ... #diagnosis
Abnormal liver function tests algorithm. This figure details the initial response to abnormal liver blood tests.
suspicious clinical symptoms ... Areas of diagnostic ... alcohol-related liver disease ... non-alcoholic fatty liver disease ... Abnormal #Algorithm #Hepatology
Leukemias Overview: ALL, CML, AML, APML, CLL Acute leukemias > 20% blasts in the peripheral blood smear
rapid onset of symptoms ... Symptoms: • Malaise ... extramedullary disease ... #Leukemia #Hematology ... #Oncology #Diagnosis
Pott's Disease in Tuberculosis - Diagnosis and Management Summary Epidemiology: - Typically from TB endemic areas -
Pott's Disease in ... decreased reflexes Pathophysiology ... of bacilli to bone ... should be done in ALL ... CMC_IM #Potts #Disease
Hemophagocytic Lymphohistiocytosis (HLH) Pathophysiology: Triggering factor (infection,...)→Activation of CD8 T cells (IFN-y) → Excessive activation of macrophages
Lymphohistiocytosis (HLH) Pathophysiology ... , Biological + Bone ... /ml, ↑ LDH • Bone ... Griscelli, Purtilo (XLP ... • Autoimmune diseases
Bell's Palsy - Diagnosis and Management Summary - GrepMed Handbook Acute Idiopathic Unilateral Facial Nerve (CN7) Palsy Presentation:
and Workup: • ... Imaging (if atypical symptoms ... middle ear/temporal bone ... pathology) • LP ... Management #Treatment #Neurology
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