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diagnosis management signs hepatology syndrome complications differential oncology msk alkaline alp anemia cirrhosis dermatology disease hemophagocytic hlh lymphohistiocytosis neurology nutrition
Causes of Thrombocytopenia and Platelet Disorders - Differential Diagnosis and Workup History: - Prior platelet count, family
pylori test (GI symptoms ... candidate) - Bone ... patients if the cause ... or if a primary hematologic ... #Workup #hematology
Low Alkaline Phosphatase - Hypophosphatasia Is Low Alkaline Phosphatase Of Clinical Importance? ALP enzyme- Discovered in 1923 Low
Most cases diagnosed ... collection with EDTA Pathophysiology ... mineralization Symptoms ... Phosphatase: • Other causes ... Hyophosphatasia #hepatology
Childhood Immunization Schedule: Why we immunize • Diphtheria Toxin -> URT inflammation causes pseudomembrane with hardened
invade URT & via hematologic ... hemorrhagic rash; symptoms ... CNS and hematologic ... non-specific viral symptoms ... peds #pediatrics #pathophysiology
Alkaline Phosphatase (ALP) Elevation - Differential Diagnosis Algorithm ALP: - Enzymes that catalyze hydrolysis of organic phosphate
- Highest • Bone ... Intestine - Other causes ... Most common symptoms ... symptoms - Pain ... Diagnosis #Algorithm #hepatology
Systemic Lupus Erythematosus (SLE): Musculoskeletal Manifestations • Immune Complex Deposition - Arthralgia, Arthritis
Weakness, Incr CK • Bone ... Myopathy (Also caused ... Complications #pathophysiology ... #signs #symptoms
Fat Embolism Syndrome Trauma to the long bone or pelvis accounts for —9096 of cases. The diagnosis
Trauma to the long bone ... accounts for —9096 of cases ... Pathophysiology ... Diagnosis #Signs #Symptoms
Leukostasis vs Tumor Lysis Syndrome Leukostasis: • Pathophysiology: Large, immature blasts and high WBC count cause hyperviscosity
Leukostasis: • Pathophysiology ... high WBC count cause ... Dehydration • Symptoms ... Lysis Syndrome: • Pathophysiology ... diagnosis #management #hematology
Pott's Disease in Tuberculosis - Diagnosis and Management Summary Epidemiology: - Typically from TB endemic areas -
extrapulmonary cases ... Clinical Signs/Symptoms ... back pain - Symptoms ... decreased reflexes Pathophysiology ... of bacilli to bone
Acute Fatty Liver of Pregnancy (AFLP) Pathophysiology: • Defect in fetal free fatty acid metabolism products →
Pregnancy (AFLP) Pathophysiology ... postpartum): • Initial symptoms ... = nonspecific (nausea ... Liver #Pregnancy #hepatology ... diagnosis #management #pathophysiology
Leukemias Overview: ALL, CML, AML, APML, CLL Acute leukemias > 20% blasts in the peripheral blood smear
rapid onset of symptoms ... chronic onset of symptoms ... B-cell lineage ALL Symptoms ... -> AML: Blast crises ... #Leukemia #Hematology
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