19 results
Osteosarcoma 
Most common primary malignant bone tumor in children 
Most Common Sites of Involvement:
1. Distal femur
primary malignant bone ... injury • Systemic symptoms ... Diagnosis #Features #Oncology
Chemotherapy Toxicity Bear Mnemonic - Cumulatively Toxic Drugs and their Rescues
 • Asparagine: neurotoxicity
 • Cisplatin:
nerves, Blast my bones ... • Bleomycin: pulmonary ... #pharmacology #oncology
Pharmacologic treatment algorithms by Global Initiative for Chronic Obstructive Lung Disease grade. Highlighted boxes and arrows
Highlighted boxes ... perceived level of symptoms ... #Management #Pulmonary
Leukemias Overview: ALL, CML, AML, APML, CLL

Acute leukemias > 20% blasts in the peripheral blood smear
blood smear or on bone ... rapid onset of symptoms ... chronic onset of symptoms ... B-cell lineage ALL Symptoms ... Leukemia #Hematology #Oncology
Pott's Disease in Tuberculosis - Diagnosis and Management Summary
Epidemiology:
 - Typically from TB endemic areas
 -
Clinical Signs/Symptoms ... back pain - Symptoms ... of active pulmonary ... of bacilli to bone ... for concomitant pulmonary
Fat Embolism Syndrome
Trauma to the long bone or pelvis accounts for —9096 of cases. The diagnosis
Trauma to the long bone ... onset widespread pulmonary ... Diagnosis #Signs #Symptoms
Mastoiditis: Pathogenesis and clinical findings

Acute or Chronic Otitis Media -> 
Stage 1: Hyperemeia of the mastoid
3: Necrosis of bone ... of the temporal bone ... inner cortical bone ... pathophysiology #signs #symptoms ... #diagnosis #otology
Prader-Willi Syndrome: Pathogenesis and clinical findings
 • Maternal uniparental disomy: inheriting 2 copies of maternal chromosome
Syndrome Signs/Symptoms ... Infertility • Decr Bone ... sleep apnea, cor pulmonale
Aplastic Anemia - Overview

Who?
• M = F
• 3 peaks:	1) Childhood	2) 15-25 years	3) >60 years

What?
• Aplastic anemia
= Hypocellular bone ... • Suggested by bone ... hypoplasia/fatty bone ... • Improve the symptoms ... Aplastic #Anemia #oncology
Highlighted Conditions With Arteritis or Periarteritis of the Coronaries
Takayasu's arteritis:
 - Onset < 40 yrs
 -
yrs - Cranial symptoms ... sinusitis - pulmonary ... Erdheim-Chester disease: - Bone