14 results
Approach to Joint Pain - Diagnostic Framework

1) Chronicity
2) Inflammatory vs Non-Inflammatory
3) Number of Joints Involved

1) Chronicity:
about bacterial infections ... infection. ... - parvovirus, HIV ... #rheumatology # ... approach #workup #differential
Causes of Bone/Joint Pain in Sickle Cell Disease
Vaso-occlusive pain:
 • Mechanism: ischemic pain
 • Can present
Causes of Bone/Joint ... common sites: hip ... • XR, MRI to dx ... • Differentiate ... diagnosis #causes #hematology
Approach to Joint Pain - Arthritis Differential Diagnosis Framework

Inflammatory Versus Noninflammatory Pain
 • Is it inflammatory
Pain - Arthritis Differential ... - Autoimmune Rheumatologic ... Parvovirus B19 • HIV ... #pain #Differential ... Diagnosis #MSK #rheumatology
Causes of Knee Effusions - Differential Diagnosis Framework

Knee Effusion Red Flags:
1. Fever/Chills/Joint pain/Night sweats/Weight loss
	- DDX:
		-
Knee Effusions - Differential ... Fever/Chills/Joint ... Weight loss - DDX ... Brucellosis - Viruses: HIV ... Effusions: - Hematologic
Adult-Onset Still's Disease
Clinical triad: Fever, Arthralgia/arthritis, Skin rash ± odynophagia
+ Biological inflammation: Increased neutrophils, Hyperferritinemia, decreased
fraction < 20% Differential ... Diaqnoses: • Infectious ... Coxsackie, CMV, EBV, HIV ... Disease #diagnosis #management ... #treatment #rheumatology
Common Variable Immunodeficiency (CVID)

What?
CVID: Immunodeficiency disorder with hypogammaglobulinemia -> increased infection risk secondary to impaired B-cell
and M panel Management ... DDX - Other causes ... Epstein-Barr syndrome, HIV ... hypogammaglobulinemia #immunology #hematology ... #diagnosis #management
Approach to Joint Pain

History:
Is the pain from:
	• Joint
	• Adjacent bursa
	• Tendon
	• Ligament
	• Bone
	• Muscle
	• Referred from
Calcium oxalate Infectious ... Acute or chronic infections ... e.g., congenital hip ... #Pain #MSK #rheumatology ... approach #workup #differential
Heparin Induced Thrombocytopenia (HIT) - Diagnosis and Management - GrepMed Handbook

Presentation: 
 • Plts ↓50% (nadir
Thrombocytopenia (HIT ... likelihood of HIT ... in 30d) • H/o HIT ... of HIT #HIT ... #Treatment #Hematology
Aplastic Anemia - Overview

Who?
• M = F
• 3 peaks:	1) Childhood	2) 15-25 years	3) >60 years

What?
• Aplastic anemia
- HIV • Immune ... and thymoma DDX ... immunodeficiency virus (HIV ... Anemia #oncology #hematology ... #diagnosis #management
Vasculitis and Vasculitides - Differential Diagnosis Framework

When to Consider Vasculitis:
 • Purpura, ischemic skin lesions
 •
vesicular eruption - Joints ... to exclude are infections ... CTD) • ANCA (Dx ... Cryoglobulins • HIV ... #diagnosis #rheumatology