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diagnosis hematology causes management oncology algorithm aplastic common cvid dermatology disorders hypogammaglobulinemia immunodeficiency immunology mds myelodysplasia myelodysplastic nonpalpable palpable platelet
Causes of Thrombocytopenia - Differential Diagnosis Algorithm Decreased Megakaryopoiesis • Aplastic Anemia • Toxic Damage (e.g.
Causes of Thrombocytopenia ... - Differential ... Megakaryopoiesis • Aplastic Anemia ... Quinidine • HIT ... Vasculitis • Infection
Causes of Thrombocytopenia and Platelet Disorders - Differential Diagnosis and Workup History: - Prior platelet count, family
Platelet Disorders - Differential ... procedures - Infection ... Risks factor for HIV ... peripheral blood smear, HIV ... changes), high MCV anemia
Aplastic Anemia - Overview Who? • M = F • 3 peaks: 1) Childhood 2) 15-25 years 3) >60 years What? • Aplastic anemia
/fevers • Thrombocytopenia ... Idiopathic • Infections ... - HIV • Immune ... and thymoma DDX ... immunodeficiency virus (HIV
Purpura - Differential Diagnosis Framework Non-blanchable, dark red to purple, hemorrhagic skin lesions that result from leakage
Purpura - Differential ... - Hemolytic anemia ... SLE) - Viral infections ... • HCV, HBV Not ... #rheumatology #
Common Variable Immunodeficiency (CVID) What? CVID: Immunodeficiency disorder with hypogammaglobulinemia -> increased infection risk secondary to impaired B-cell
• Avg age of DX ... specifically immune thrombocytopenia ... autoimmune hemolytic anemia ... DDX - Other causes ... Epstein-Barr syndrome, HIV
Myelodysplastic Syndromes (MDS) What? Myelodysplastic syndromes are a group of disorders caused by blood cells that are poorly
platelet count (thrombocytopenia ... petechiae) • Frequent infections ... DDX: Rule Out ... • Parvovirus infection ... blood count with differential
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