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management multiple sclerosis aids algorithm alice associated bee causes clinical criteria dementia disorder encephalopathy half hand headache hiv hp hypertrophic
CNS Ring-Enhancing Lesions - Immunocompromised vs Immunocompetent Multiple Ring-Enhancing Lesions: • Toxoplasmosis (CD4 < 100) • Other
- Compatible syndrome ... + MRI lesions + ... #Brain #differential ... #diagnosis #causes ... #radiology #neurology
McDonald Criteria for Diagnosis of Multiple Sclerosis • 2 or more attacks, 2 or more lesions
attacks, 2 or more lesions ... more attacks, 1 lesion ... • 1 attack, 2 lesions ... • 1 attack, 1 lesion ... Multiple #Sclerosis #MS
BEE Syndromes - Non-inflammatory Causes Immune-mediated conditions affecting the Brain, Eye, and Ear Visual or auditory symptoms in
affecting the Brain ... nervous system (CNS ... lesions and clinical ... consistent with MS ... #differential #
Weakness - Differential Diagnosis Framework Approach To Weakness: • Non-neuromuscular disorder (Cardiac, pulmonary etc) • CNS ->
pulmonary etc) • CNS ... Space occupying lesions ... tumor • Lesions ... Lesions Of The Peripheral ... #Diagnosis #neurology
Alice in Wonderland Syndrome What? Metamorphophsia - Distortions of the visual perceptions with changes in size (micro
• CNS: parietal ... encephalitis) • Brain ... lesions (e.g. stroke ... #diagnosis #neurology ... #differential
Multiple Sclerosis - Summary Multiple Sclerosis (MS) is an autoimmune-mediated neurodegenerative disease of the central nervous system
Multiple Sclerosis (MS ... • Or brainstem syndromes ... demyelinating lesions ... resonance imaging [MRI ... ] T2 lesions) McDonald
Approach to Headaches - Differential Diagnosis Algorithm Red flags (PHANTOMS): • Pattern change, progressively worse, papilledema •
Diagnosis Algorithm ... papilledema • Horner syndrome ... Space-occupying brain ... lesion • CNS ... #neurology #PHANTOMS
Transverse Myelitis Overview Focal inflammatory disorder of the spinal cord resulting in rapid onset of weakness, sensory
10-33% develop MS ... compressive cord lesion ... less swollen - Lesion ... Predictive of MS ... nerve lesions suggestive
HIV-Associated Neurocognitive Disorder (HAND) Definition: HIV-Associated Neurocognitive disorders categories: • Asymptomatic neurocognitive impairment • Mild neurocognitive impairment • HIV dementia Pathophysiology: HIV frequently
bilateral white matter lesions ... well-defined than PML lesions ... Diagnosis: MRI ... The clinical syndrome ... dementia #AIDS #Neurology
Neurological Manifestations of Tuberculosis Spinal Arachnoiditis & Polyradiculopathy: • Subacute onset of limb weakness, bladder/bowel dysfunction, muscle
ring-enhanced lesion ... contrast enhancement Brain ... ring-enhancement lesion ... #Tuberculosis #diagnosis ... #differential #
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