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diagnosis pathophysiology gh growthhormone signs excess features feedbackloop hypothyroid management overproduction physicalexam pituitary treatment
Feedback Loop: Growth Hormone (GH) Growth Hormone: • Liver -> GHR activates JAK-STAT pathway -> Incr IGF1
chondrocytes -> Incr ossification ... lipolysis Signs/Symptoms ... - Giantism or acromegaly ... expansion (e.g. carpal ... #FeedbackLoop #endocrinology
Growth Hormone Excess - Pathogenesis and clinical findings • Acromegaly and gigantism share the same pathophysiology
clinical findings • Acromegaly ... overgrowth: • Carpal ... Tunnel Syndrome ... diagnosis #signs #symptoms ... #endocrinology
Acromegaly - Diagnosis and Management Summary - GrepMed Handbook Clinical Presentation: • Classic Acromegaly: frontal
Acromegaly - Diagnosis ... paresthesias (carpal ... decade → peripheral/acral ... Beckwith Wiedemann syndrome ... Diagnosis #Management #Endocrinology
Hypothyroidism – symptoms and signs. Symptoms: Tiredness/malaise, Weight gain, Anorexia, Cold intolerance, Poor memory, Change in appearance, Depression, Poor libido,
Hypothyroidism – symptoms ... Symptoms: Tiredness ... peripheries, Carpal ... timel syndrome, ... #PhysicalExam #Endocrinology
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