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diagnosis management tb hematology latenttb differential disease hemeonc hemophagocytic hlh leukostasis lymphohistiocytosis lysis night potts sarcoidosis sjogrens summary sweats symptoms
Tuberculosis Overview 10 million new M. tuberculosis infections/year Facultative intracellular rod-shaped bacteria Multidrug-resistant tuberculosis (MDR-TB) accounts for 4.6% of
(LTBI) Pathophysiology ... Immunosuppression • Tumor ... Treatment: Active ... Initiating Treatment ... Diagnosis #Management #Treatment
Tuberculosis Overview 10 million new M. tuberculosis infections/year Facultative intracellular rod-shaped bacteria Multidrug-resistant tuberculosis (MDR-TB) accounts for 4.6% of
(LTBI) Pathophysiology ... Immunosuppression • Tumor ... Treatment: Active ... Initiating Treatment ... Diagnosis #Management #Treatment
Leukostasis vs Tumor Lysis Syndrome Leukostasis: • Pathophysiology: Large, immature blasts and high WBC count cause hyperviscosity
Leukostasis: • Pathophysiology ... high WBC count cause ... WBC >100k, + lab signs ... • Pathophysiology ... diagnosis #management #hematology
Pott's Disease in Tuberculosis - Diagnosis and Management Summary Epidemiology: - Typically from TB endemic areas -
extrapulmonary cases ... Clinical Signs ... /symptoms of active ... pulmonary TB PE ... decreased reflexes Pathophysiology
Sarcoidosis - Diagnosis and Management Summary Epidemiology 1) High incidence in Scandinavian countries (11-24 cases per 100,000 individuals
survival is 93-95% Pathophysiology ... increased B-cell activity ... symptoms are not caused ... Pulmonary: dyspnea ... Diagnosis #Management #Signs
Causes of Night Sweats - Differential Diagnosis • Malignancy: Lymphoma, Leukemia, Other neoplasm • Infections: Human
Causes of Night ... immunodeficiency virus, tuberculosis ... Orchiectomy • Rheumatologic ... Chronic fatigue syndrome ... Autonomic over-activity
Sjogren's Syndrome Overview Epidemiology: • F > M: 9:1 • 5-6th Decades (can be any age) Autoimmune exocrinopathy multisystemic disease
Hypocomplementemia • Can cause ... , INC risk PE, Pulmonary ... Adenocarcinoma Treatment ... muscarinic agonists • Active ... #Rheumatology #
Hemophagocytic Lymphohistiocytosis (HLH) High mortality without prompt recognition and management. HLH is a critical diagnostic consideration in
caused by uncontrolled ... Presentation • Common Signs ... Pathophysiology ... absent NK-cell activity ... Diagnosis #Management #Hematology
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