56 results
Retinoblastoma: Pathogenesis and clinical findings
 • Sporadic mutation -> One allele of RB1 tumor suppressor gene
Pathogenesis and clinical ... allele of RB1 tumor ... allele of RB1 tumor ... pathophysiology #ophthalmology ... #symptoms
Leukostasis vs Tumor Lysis Syndrome
Leukostasis:
 • Pathophysiology: Large, immature blasts and high WBC count cause hyperviscosity
Leukostasis vs Tumor ... WBC >100k, + lab signs ... /- rasburicase Tumor ... rate or large tumor ... #Leukostasis #Tumor
Clinical Manifestations of Serotonin Syndrome
 • Ophthalmologic: Mydriasis, Ocular clonus (slow horizontal movements)
 • Gastrointestinal: Diarrhea,
Clinical Manifestations ... of Serotonin Syndrome ... • Ophthalmologic ... #Symptoms #spectrum ... #signs #diagnosis
Brudzinski's sign is a physically demonstrable symptom of meningitis. It is characterized by reflexive flexion of
Brudzinski's sign ... physically demonstrable symptom ... #Brudzinskis #sign ... #clinical #video ... #neurology #meningitis
Important Causes of Diplopia 
TIER 1-CRITICAL
Basilar artery thrombosis, Botulism, Basilar meningitis, Aneurysmn
TIER 2-EMERGENT:
Vertebral dissection, Myasthenia gravis,
Diplopia TIER 1-CRITICAL ... , Orbital apex syndrome ... URGENT: Brainstem tumor ... Miller-Fisher syndrome ... differential #diagnosis #ophthalmology
Simultagnosia on Physical Exam (Balint Syndrome)

The patient can recognize objects one at a time but cannot
Physical Exam (Balint Syndrome ... Simultagnosia #Balint #Syndrome ... #PhysicalExam #clinical ... #video #neurology ... #ophthalmology
Horner's Syndrome: Loss of sympathetic nervous system input to (in this case) right eye. 
Note that
Horner's Syndrome ... case was due to tumor ... UCSD Catalog of Clinical ... Images #Clinical ... #Ophthalmology
Carotid Blowout Syndrome (CBS) on Physical Examination

Carotid blowout syndrome in a patient with late-stage oral tongue
Carotid Blowout Syndrome ... recurrent or second tumor ... infection, or direct tumor ... #CBS #clinical ... #video #PhysicalExam
Keratoconus: Pathogenesis and Clinical Findings
Genetics
 • Family history of keratoconus
 • Ehlers-Danlos syndrome
 • Down, Turner,
Pathogenesis and Clinical ... • Down, Turner ... , Marfan syndromes ... / Symptoms / Complications ... pathophysiology #ophthalmology
Effects of Strokes by Location - Anterior vs Posterior Localization

Anterior Circulation 
 - MCA 
 -
Artery #Strokes #Syndromes ... CVA #Territory #Symptoms ... #Signs #Localization ... Comprehensive Review in Clinical ... Neurology - https