44 results
Pituitary Mass Effects - Pathogenesis and Clinical Findings
 • Pituitary turnors are almost always a benign
• Pituitary turnors ... adenomas that require treatment ... the pituitary tumor ... Signs / Symptoms ... #SideEffects #endocrinology
Congenital Adrenal Hyperplasia - 21-Hydroxylase Deficiency - Signs and Symptoms
 • Brain: Androgenization effects, Glucocorticoid effects,
Hydroxylase Deficiency - Signs ... hyperplasia and tumors ... , Adrenal rest tumor ... Hydroxylase #Deficiency #Signs ... Symptoms #diagnosis #endocrinology
Leukostasis vs Tumor Lysis Syndrome
Leukostasis:
 • Pathophysiology: Large, immature blasts and high WBC count cause hyperviscosity
Leukostasis vs Tumor ... WBC >100k, + lab signs ... /- rasburicase Tumor ... rate or large tumor ... #Leukostasis #Tumor
Parinaud's Syndrome
What?
 - Impaired upgaze
 - Light-near dissociation
 - Convergence retraction nystagmus
 - Eyelid retraction (Collier's
retraction (Collier's sign ... Pineal region tumors ... → "setting sun sign ... diagnosis #pineal #neurology
Malignant Bone Tumors: Pathogenesis of X-ray appearance

 • Metastatic bone tumors (aka. cancerous cells from systemic
Malignant Bone Tumors ... Metastatic bone tumors ... Signs/Symptoms: ... between bone and tumor ... around the bone tumor
Woltman’s sign on Physical Exam

53-year-old man presented with fatigue and sensitivity to cold. A physical examination
Woltman’s sign on ... reflex — Woltman’s sign ... Woltman’s sign, ... #Woltmans #Signs ... #Endocrinology
Retinoblastoma: Pathogenesis and clinical findings
 • Sporadic mutation -> One allele of RB1 tumor suppressor gene
allele of RB1 tumor ... allele of RB1 tumor ... Retinoblastoma Signs ... ophthalmology #diagnosis #signs
Diagram of different types of bone tumors that can occur around the knee on XRay -
types of bone tumors ... • Giant cell tumor ... blade of grass sign ... #Knee #Bone #Tumors
Multiple Sclerosis - Summary

Multiple Sclerosis (MS) is an autoimmune-mediated neurodegenerative disease of the central nervous system
Forms of MS: • Tumor-like ... Clonus, Babinski’s sign ... • Lhermitte’s sign ... pupillary defect SIGNS ... Signs and symptoms
Parinaud's syndrome
What?
 • Light-near dissociation (tectal pupils)
 • Convergence retraction nystagmus
 • Eyelid retraction (Collier's sign)
retraction (Collier's sign ... Pineal region tumors ... "setting sun" sign ... Parinauds #syndrome #neurology