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management hematology lysis behcet disease emergencies hemeonc leukemia oncologic signs symptoms
Leukostasis vs Tumor Lysis Syndrome Leukostasis: • Pathophysiology: Large, immature blasts and high WBC count cause hyperviscosity
Leukostasis vs Tumor ... /- rasburicase Tumor ... rate or large tumor ... #Tumor #Lysis # ... Syndrome #TLS #diagnosis
Tumor Lysis Syndrome - Workup and Management Initial workup: BMP, Serum uric acid, LDH, Urine output, Consider
Tumor Lysis Syndrome ... ICU transfer • Tumor ... #Tumor #Lysis # ... Syndrome #diagnosis ... #management #oncology
Summary of Oncologic Emergencies Neutropenic fever: - Fever + ANC < 500 → start cefepime ± vancomycin (if
antibiotics TLS ... (tumor-lysis syndrome ... low Ca - q8 h TLS ... anticoagulation Leukostasis ... #HemeOnc #Diagnosis
Behçet's Syndrome Systemic disease associated with inflammation of multiple organs, small-vessel vasculitis and large-vessel vasculopathy Epidemiology: • Young
/IVC occlusion, ... ) Differential Diagnosis ... interferon alfa, or tumor ... inhibitors • Uveitis- Ophthalmology ... signs #symptoms #rheumatology
Leukemias Overview: ALL, CML, AML, APML, CLL Acute leukemias > 20% blasts in the peripheral blood smear
↑ Can develop leukostasis ... syndrome: CNS manifestations ... Fibrinolysis & DIC • Tumor ... lysis syndrome: ... #Oncology #Diagnosis
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