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diagnosis hematology differential management leukemia treatment workup chronic classification dermatology globulin hodgkins lymphocytic lymphoma mds myelodysplasia myelodysplastic pheochromocytoma platelet protein
Leukemias Overview: ALL, CML, AML, APML, CLL Acute leukemias > 20% blasts in the peripheral blood smear
ALL Symptoms: ... extramedullary disease ... activity • ↓ LAP ... ) CLL Symptoms: ... #Oncology #Diagnosis
Causes of Thrombocytopenia and Platelet Disorders - Differential Diagnosis and Workup History: - Prior platelet count, family
PT, aPTT(liver disease ... pylori test (GI symptoms ... neurologic/psychiatric changes ... not required in all ... #Workup #hematology
Chronic Lymphocytic Leukemia - Summary Cancer affecting lymphocytes/Mature B cell neoplasm • Lymphocytes accumulate in large numbers
with no early symptoms ... Physical Exam/Signs ... cells can indicate disease ... lymphoproliferative disorders ... diagnosis #workup #oncology
Chagas Disease - American Trypanosomiasis - Diagnosis and Management Summary Chagas disease (American trypanosomiasis) is an infectious
Chagas Disease - ... caused by the protozoan ... Romana's sign ... /symptoms, positive ... Cardiomyopathy: Conduction disorders
Elevated Globulin - Protein Gap (Total Protein - Albumin > 4) Work-up of an Elevated Globulin Gap: •
• Heavy chain disease ... gammopathy, and skin changes ... plasmacytoma • Castleman disease ... Connective tissue disorders ... Sarcoidosis) • Liver disease
Myelodysplastic Syndromes (MDS) What? Myelodysplastic syndromes are a group of disorders caused by blood cells that are poorly
are a group of disorders ... age 70 years Symptoms ... Myeloproliferative Disease ... cells have DNA changes ... #oncology
Sweet Syndrome Acute febrile neutrophilic dermatosis (Sweets Syndrome) is a skin condition characterized by fever and inflamed
with systemic disease ... Rare Disorder: ... Episcleritis Signs ... Causes: - Idiopathic ... #dermatology #oncology
Pheochromocytoma - Diagnosis and Management Summary 10 percent rule = 10% of pheochromocytomas are extra-adrenal, multiple, bilateral,
bilateral, malignant, pediatric ... and Signs: 50% ... mental status changes ... leukocytosis, psychiatric disorders ... Treatment • Operable disease
Hodgkin's Lymphoma Overview Hodgkin's lymphoma (HL) is an uncommon hematological malignancy arising from mature B cells. It
accounts for 10% of all ... • Autoimmune disorders ... ingestion • B symptoms ... number of sites of disease ... #oncology #management
Vasculitis - Differential Diagnosis Framework When to Consider Vasculitis: • Purpura, ischemic skin lesions • Mononeuritis multiplex • Hematuria, proteinuria,
Presentation: Systemic Symptoms ... purpura: Strong sign ... • Progressive symptoms ... and gray matter changes ... tract, and often causes
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