24 results
Osteoporosis: Pathogenesis and risk factors

 • Age > 30 (post-peak bone mass)
 • Post-menopausal women ->
30 (post-peak bone ... Decr estrogen • Bone ... Corticosteroid use • Primary ... #Osteoporosis #pathophysiology ... #signs #symptoms
Diagram of different types of bone tumors that can occur around the knee on XRay -
Diagram of different types ... phase • Paget disease ... blade of grass sign ... #Differential # ... Radiology #XRay #msk
Gaucher Disease 

Pathophsiology
 • Lysosomal storage disorder
 • Deficiency of ß-glucocerebrosidase
• Accumulation of glucosylceramide in macrophages
Diagnosis
Pathophsiology ... Neurological involvement (type ... Osteonecrosis, bone ... #Diagnosis #Signs ... #Symptoms
Pathologic / Fragility Fractures - Differential Diagnosis Algorithm 
Tumours
 - See Bone Lesions Scheme
Paget's Disease
 -
Tumours - See Bone ... Phosphate Deficiency Primary ... • Bone Marrow ... Malignancy • Drugs (e.g ... Fractures #Pathologic #MSK
Hodgkin's Lymphoma vs Non-Hodgkin's Lymphoma - Comparison

Hodgkin's Lymphoma:
 • Epidemiology: young adults 20-30, older 50-70
 •
- B symptoms ... translocation • Types ... on: - Cell type ... involvement Differential ... oncology #diagnosis #differential
Diagram of different types of bone tumors that can occur around the knee on XRay
Age <
Diagram of different types ... phase • Paget disease ... blade of grass sign ... #Differential # ... Radiology #XRay #MSK
Meralgia paresthetica: Pathogenesis and Clinical Findings
Compression/injury of Lateral Femoral Cutaneous Nerve (LFCN) -> Meralgia paresthetica
 •
intervertebral disc disease ... MeralgiaParesthetica #MSK ... #pathophysiology ... #differential # ... diagnosis #signs
Multiple Sclerosis - Summary

Multiple Sclerosis (MS) is an autoimmune-mediated neurodegenerative disease of the central nervous system
neurodegenerative disease ... /SYMPTOMS: • CENTRAL ... Signs and symptoms ... • Primary Progressive ... /or cerebellar symptoms
Primary Biliary Cirrhosis (PBC) - Summary

PBC Epidemiology:
 • Female:Male 9:1
 • Common European descent
 • Age:
Primary Biliary ... 65 years PBC Pathophysiology ... failure PBC Signs ... and Symptoms: ... bile ducts Differential
Approach to Joint Pain

History:
Is the pain from:
	• Joint
	• Adjacent bursa
	• Tendon
	• Ligament
	• Bone
	• Muscle
	• Referred from
• Ligament • Bone ... or nerve root Symptoms ... the subchondral bone ... #Joint #Pain #MSK ... approach #workup #differential