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management algorithm aplastic cancer centralretinalartery chronic crao crisis dermatology erythematosus gap globulin lupus lymphocytic myelodysplasia myelodysplastic nephrology occlusion ophthalmology pathophysiology
Leukemias Overview: ALL, CML, AML, APML, CLL Acute leukemias > 20% blasts in the peripheral blood smear
APML, CLL Acute ... extramedullary disease ... - infiltrates (anemia ... #Hematology #Oncology ... #Diagnosis
Chronic Lymphocytic Leukemia - Summary Cancer affecting lymphocytes/Mature B cell neoplasm • Lymphocytes accumulate in large numbers
with no early symptoms ... Physical Exam/Signs ... • Neutropenia, anemia ... ’s lymphoma or acute ... #oncology #hematology
Myelodysplastic Syndromes (MDS) What? Myelodysplastic syndromes are a group of disorders caused by blood cells that are poorly
age 70 years Symptoms ... Pinpoint-sized red spots ... Cell Leukemia ... #diagnosis #hematology ... #oncology
Aplastic Anemia - Overview Who? • M = F • 3 peaks: 1) Childhood 2) 15-25 years 3) >60 years What? • Aplastic anemia
Marrow (Toxic injury ... Clinical Presentation ... and petechiae Causes ... virus (EBV) • Leukemia ... #oncology #hematology
Sweet Syndrome Acute febrile neutrophilic dermatosis (Sweets Syndrome) is a skin condition characterized by fever and inflamed
Acute febrile ... with systemic disease ... Episcleritis Signs ... #diagnosis #dermatology ... #oncology
Central Retinal Artery Occlusion: Pathogenesis and clinical findings • Inflammatory Disease: (i.e. GCA, SLE, GPA) ->
Pathogenesis and clinical ... leukemia/lymphoma ... -> Cherry-red spot ... trucking" • Acute ... #signs #symptoms
SLE (Systemic Lupus Erythematosus) Suspect: Clinical evidence of (fatigue, rash, photosensitivity, inflammatory arthritis, weight loss, and fever) and
permanent alopecia Differential ... • Type-I Interferonopathies ... Induced Lupus: • Symptoms ... Hodgkin lymphoma and leukemia ... #Rheumatology
Scleroderma Renal Crisis (SRC) Clinical Presentation of Scleroderma Renal Crisis: 1) Acute kidney injury 2) Abrupt onset of hypertension 3)
Crisis (SRC) Clinical ... Renal Crisis: 1) Acute ... kidney injury ... microangiopathic hemolytic anemia ... Renal #Crisis #rheumatology
Elevated Globulin - Protein Gap (Total Protein - Albumin > 4) Work-up of an Elevated Globulin Gap: •
changes (POEMS syndrome ... gastric tumors • Hematology ... anemia • Other ... Comment on type ... #diagnosis #hematology
Myelodysplastic syndromes current treatment algorithm 2018. From Blood Cancer Journal, Published 24 May 2018 Myelodysplastic syndromes (MDS) are
clonal evolution to acute ... myeloid leukemia ... median age at diagnosis ... tolerate anemia ... #algorithm #hematology
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