32 results
Gaucher Disease 

Pathophsiology
 • Lysosomal storage disorder
 • Deficiency of ß-glucocerebrosidase
• Accumulation of glucosylceramide in macrophages
Diagnosis
Gaucher Disease ... Pathophsiology ... in GBA1 gene Clinical ... Neurological involvement (type ... #Diagnosis #Signs
Clinical Classification of Pulmonary Hypertension

1. Pulmonary arterial hypertension from pulmonary vasculopathy
Idiopathic pulmonary arterial hypertension
Heritable gene mutations
Clinical Classification ... protein receptor type ... activin A receptor type ... Interstitial lung ... Classification #Diagnosis #Differential
Pott's Disease in Tuberculosis - Diagnosis and Management Summary
Epidemiology:
 - Typically from TB endemic areas
 -
Pott's Disease in ... extrapulmonary cases Clinical ... Signs/Symptoms: ... years - May have signs ... decreased reflexes Pathophysiology
Bilateral B-Lines in case of Pneumonia on Lung POCUS

Young healthy pt with fever/dyspnea. POCUS lung exam
Differential Bilat ... Pulmonary edema, ARDS, interstitial ... lung disease, interstitial ... partially seen shred sign ... #Lung #POCUS #clinical
Prader-Willi Syndrome: Pathogenesis and clinical findings
 • Maternal uniparental disomy: inheriting 2 copies of maternal chromosome
Pathogenesis and clinical ... Prader-Willi Syndrome Signs ... fractures • Short ... • Obesity -> Type ... Syndrome #genetics #pathophysiology
Penicillin Allergy Pathway for Antibiotic Prescription in Patients With Penicillin Allergy
Mild Reaction - Itching, Minor rash
If infectious disease ... necrolysis, Acute interstitial ... there is a strong clinical ... and Infectious Disease ... Prescription #algorithm #management
Keratoconus: Pathogenesis and Clinical Findings
Genetics
 • Family history of keratoconus
 • Ehlers-Danlos syndrome
 • Down, Turner,
Pathogenesis and Clinical ... Changes in collagen types ... rubbing • Atopic diseases ... • Rizutti's Sign ... #Keratoconus #pathophysiology
Sjogren's Syndrome Overview

Epidemiology:
• F > M: 9:1
• 5-6th Decades (can be any age)

Autoimmune exocrinopathy multisystemic disease
Hypocomplementemia • Can cause TYPE ... IV RTA, TYPE I ... salivary ducts Clinical ... nephritis • Distal (Type ... Rheumatology #Diagnosis #Management
Nail Pathologies - Findings in or Near Nails

Paronychia 

A superficial infection of the proximal and lateral
the Fingers Clinically ... , interstitial lung ... Spots in the pattern ... Pathology #Diagnosis #Clinical ... #Signs #PhysicalExam
Lung Abscess - Diagnosis and Management Summary

Lung Abscess Etiology:
 • Necrosis of lung parenchyma by a
Diagnosis and Management ... Lung Abscess Pathophysiology ... Lung Abscess - Clinical ... Lung Abscess Differential ... Abscess #pulmonary #differential