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vasculitis comparison dermatomyositis management agglutinin anemia antimda5 antinxp2 antinxp2dm classification clinical cold compared dermpath erythemas erythematosus hemolytic hodgkins lesions lupus
Dermatological semiology of Cutaneous Vasculitis Clinicopathologic correlations • Purpura, papules, pustules, necrosis: involvement of small vessels
Identification of causes ... Connective tissue disease ... Vasculitis #dermpath #dermatology ... #semiology #signs ... #lesions #diagnosis
ANTI-MDA5 DERMATOMYOSITIS Cutaneous manifestations: • Periorbital heliotrope (blue-purple) rash with edema • Erythematous rash on the face, or the
chest (in a V-sign ... shoulders (in a shawl sign ... Inverse Gottron’s sign ... #rheumatology # ... dermatology #diagnosis
Hodgkin's Lymphoma vs Non-Hodgkin's Lymphoma - Comparison Hodgkin's Lymphoma: • Epidemiology: young adults 20-30, older 50-70 •
EBV infection, Autoimmune ... diseases • Clinical ... : GI, neuro, cutaneous ... #differential # ... hematology
Sjogren's Syndrome Overview Epidemiology: • F > M: 9:1 • 5-6th Decades (can be any age) Autoimmune exocrinopathy multisystemic disease
TYPE IV RTA, TYPE ... salivary ducts Clinical ... skin (xerosis) • Cutaneous ... Nephrogenic DI Hematologic ... Sjogrens #Syndrome #Rheumatology
Cold Agglutinin Disease 3 Types of Cold Sensitive Antibodies: 1. Cold Agglutinins (CAD) 2. Donath-Landsteiner
3 Types of Cold ... Viral Infection Clinical ... presentation) • Cutaneous ... pts) Differential ... hemolytic #anemia #hematology
Erythemas Summarized Erythema ab igne • A dermatosis that results from repeated exposure to heat (fires, heating
form of delayed-type ... : infections (cutaneous ... shows numerous eosinophils ... comparison #table #differential ... #diagnosis #dermatology
SLE (Systemic Lupus Erythematosus) Suspect: Clinical evidence of (fatigue, rash, photosensitivity, inflammatory arthritis, weight loss, and fever) and
) Suspect: Clinical ... permanent alopecia Differential ... rheumatologic diseases ... • Type-I Interferonopathies ... #Rheumatology
Vasculitis and Vasculitides - Differential Diagnosis Framework When to Consider Vasculitis: • Purpura, ischemic skin lesions •
• EGPA: - Eosinophilia ... tract, and often causes ... inflammatory lesions-interstitial ... purpura: strong sign ... #diagnosis #rheumatology
Vasculitis - Differential Diagnosis Framework When to Consider Vasculitis: • Purpura, ischemic skin lesions • Mononeuritis multiplex • Hematuria, proteinuria,
Diagnosis Framework ... purpura: Strong sign ... tract, and often causes ... inflammatory lesions - interstitial ... #Diagnosis #Rheumatology
Autoimmune Myositis - Differential Diagnosis Framework Inflammatory Myopathies: Commonly symmetric proximal muscle weakness, no substantial muscle pain
- Differential ... papules and Gottron sign ... ) • Shawl sign ... statins - probably caused ... Myositis #Myopathy #rheumatology
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