10 results
Adult-Onset Still's Disease
Clinical triad: Fever, Arthralgia/arthritis, Skin rash ± odynophagia
+ Biological inflammation: Increased neutrophils, Hyperferritinemia, decreased
Adult-Onset Still's ... arthritis, Skin rash ... Complications: MAS ... hepatitis • Pulmonary ... #management #treatment
Adult-Onset Still's Disease (AOSD)
Rare inflammatory disorder of unknown etiology, difficult to diagnose because of heterogenous presentation.
Adult-Onset Still's ... salmon-colored maculopapular ... rash, arthritis ... BrighamChiefs #AdultOnset ... #management #treatment
Drug Reaction with Eosinophilia and Systemic Symptoms (DRESS)
Definition: 
 • Severe adverse drug reaction, characterized by
extensive skin rash ... • Maculopapular ... eruption that may ... DRESS #Syndrome #dermatology ... #diagnosis #management
Erythematous Rashes - THE ALGORITHMIC APPROACH

Characterized by diffuse redness of the skin due to
capillary congestion, erythematous
usually to TEN in adults ... erythematous rash ... Nikolsky sign may ... #Diagnosis #Dermatology ... #Erythematous #Rash
Adult Onset Still's Disease
Systemic inflammation with urticarial rash.
Rash: 
 • Nonpruritic, evanescent (correlates with time of
Adult Onset Still's ... nonpruritic macular or maculopapular ... mL Gf consider MAS ... anti-lL6R, anti-ILI #Adult ... #rheumatology #management
Blood Transfusion Reactions

Immune Mediated:
 • Febrile Non-Hemolytic Transfusion Reaction (FNHTR): Most common immune reaction to transfusion.
Blood Transfusion Reactions ... /sx urticaria, maculopapular ... rash, pruritis, ... #Transfusion #diagnosis ... #management #hematology
Blood Product Transfusions One Pager Summary
Type and screen - determines blood type and detects in recipient
/sx urticaria, maculopapular ... rash, pruritis, ... #Transfusions #diagnosis ... #management #hematology ... #reactions
Macrophage Activation Syndrome (MAS)
Classified among the secondary or acquired forms of haemophagocytic lymphohistiocytosis (sHLH)

What?
A subset of
arthritis (sJIA) • Adult-onset ... manifestation of MAS ... Petechial or purpuric rash ... Activation #Syndrome #Diagnosis ... #Management #Hematology
Vasculitis - Differential Diagnosis Framework

When to Consider Vasculitis:
• Purpura, ischemic skin lesions
• Mononeuritis multiplex
• Hematuria, proteinuria,
- Differential Diagnosis ... Vasculitis Differential Diagnosis ... disease, drug reactions ... , mucositis • Rash ... vesicles, pustules, maculopapular
Monkeypox

What?
Monkeypox virus belongs to the family Poxviridae, subfamily Chordopoxvirinae, and genus orthopoxvirus
Viral zoonotic disease that is
both children and adults ... Typically has ... Polymerase chain reaction ... Monkeypox #MPOX #Diagnosis ... #Management #Dermatology