11 results
Skin Conditions Associated with Joint Pain

Rash
	• Human parvovirus B19 infection

Malar rash
	• SLE
	• Human parvovirus B19 infection
	•
• Rheumatic fever ... Crohn's disease Palpable ... Antiphospholipid-antibody syndrome ... Sarcoidosis #dermatology ... #differential #diagnosis
Erythematous Rashes - THE ALGORITHMIC APPROACH

Characterized by diffuse redness of the skin due to
capillary congestion, erythematous
staphylococcal scalded skin syndrome ... and toxic shock syndrome ... rash but without ... #Diagnosis #Dermatology ... Rash #Algorithm
Dermatologic Manifestations of Granulomatosis with Polyangiitis (GPA)

Skin involvement in granulomatosis with polyangiitis (GPA) is common and
• Petechiae, Palpable ... Maculopapular rash ... • Petechiae • Palpable ... • Goodpasture syndrome ... #rash #diagnosis
Purpura - Differential Diagnosis Framework

Non-blanchable, dark red to purple, hemorrhagic skin lesions that result from leakage
- Differential Diagnosis ... - Hemolytic anemia ... Kasabach-Merritt syndrome ... mountain spotted fever ... #dermatology
Clinical Features of Systemic Lupus (SLE)
General: Fever (50%), Depression, Fatigue (75%), Weight loss (50%)
Eye: Sjögrens (15%)
Skin
(SLE) General: Fever ... Photosensitivity, Butterfly rash ... Demyelinating syndromes ... ) Blood (75%): Anemia ... signs #symptoms #diagnosis
SLE (Systemic Lupus Erythematosus)

Suspect:
Clinical evidence of (fatigue, rash, photosensitivity, inflammatory arthritis, weight loss, and fever) and
weight loss, and fever ... Differential Diagnosis ... lymphopenia, low PLT • Anemia ... to: Arthritis, Fever ... #Diagnosis #Rheumatology
Macrophage Activation Syndrome (MAS)
Classified among the secondary or acquired forms of haemophagocytic lymphohistiocytosis (sHLH)

What?
A subset of
Systemic lupus erythematosus ... Petechial or purpuric rash ... systemic lupus erythematosus ... with leukopenia, anemia ... #Diagnosis #Management
Vasculitis and Vasculitides - Differential Diagnosis Framework

When to Consider Vasculitis:
 • Purpura, ischemic skin lesions
 •
Coronary arteries - Fever ... mucositis - Rash ... Vasculitis: • Fevers ... scleritis • Palpable ... Skin -> causing palpable
Vasculitis - Differential Diagnosis Framework

When to Consider Vasculitis:
• Purpura, ischemic skin lesions
• Mononeuritis multiplex
• Hematuria, proteinuria,
- Differential Diagnosis ... Vasculitis: • Fevers ... and branches • Fever ... ischemia • Skin: Erythematous ... , mucositis • Rash
Lung Infections in HIV - Differential Diagnosis Framework

Disease by CD4 Count:
Any CD4 Count:
 • Mycobacterium tuberculosis,
- Differential Diagnosis ... Pneumonia: • 3 syndromes ... papules, pustules, erythematous ... 100% of cases), anemia ... Infections #HIV #AIDS #pulmonary