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rheumatology differential hematology vasculitis clinical skinrash apml classification differentiation dress eschar hand hemophagocytic hlh joint lcv leukocytoclastic lymphohistiocytosis macrophage mas
Skin Conditions Associated with Joint Pain Rash • Human parvovirus B19 infection Malar rash • SLE • Human parvovirus B19 infection •
• Rheumatic fever ... Crohn's disease Palpable ... Antiphospholipid-antibody syndrome ... Sarcoidosis #dermatology ... #differential #diagnosis
Macrophage Activation Syndrome (MAS) Classified among the secondary or acquired forms of haemophagocytic lymphohistiocytosis (sHLH) What? A subset of
Macrophage Activation ... Petechial or purpuric rash ... MAS #Macrophage #Activation ... #Syndrome #Diagnosis ... #Management #Hematology
Vasculitis - Differential Diagnosis Framework When to Consider Vasculitis: • Purpura, ischemic skin lesions • Mononeuritis multiplex • Hematuria, proteinuria,
- Differential Diagnosis ... Vasculitis Differential Diagnosis ... Vasculitis: • Fevers ... and branches • Fever ... , mucositis • Rash
Drug Reaction with Eosinophilia and Systemic Symptoms (DRESS) Definition: • Severe adverse drug reaction, characterized by
extensive skin rash ... Fever >38.5 2. ... SinaiBmoreIMRes #DRESS #Syndrome ... #dermatology #diagnosis ... #management
Hemophagocytic Lymphohistiocytosis (HLH) Definition: Overwhelming clinical syndrome associated with excessive macrophage activation and cytokine storm due to
Overwhelming clinical syndrome ... excessive macrophage activation ... following: • Fever ... #management #treatment ... #hematology
Vasculitis and Vasculitides - Differential Diagnosis Framework When to Consider Vasculitis: • Purpura, ischemic skin lesions •
Coronary arteries - Fever ... mucositis - Rash ... Vasculitis: • Fevers ... scleritis • Palpable ... Skin -> causing palpable
Differentiation Syndrome in APML Epidemiology: • Incidence: common in APL (2-48% depending on the study) • Triggers:
Differentiation Syndrome ... Subacute-Acute: • Common: fever ... Imaging: CXR- pulmonary ... Differentiation #Syndrome ... #management #hematology
Vancomycin induced Leukocytoclastic Vasculitis (LCV) of the Hand 70 M vertebral osteomyelitis on vancomycin and cefepime for
Presents with diffuse palpable ... rash. ... Diagnosis? ... Hand #skinrash #dermatology ... #clinical #photo
Rickettsialpox Eschar 40 homeless male from NY admitted with fever, chills, headache, myalgias. Diagnosis? Rickettsialpox R akari classic
admitted with fever ... Diagnosis? ... Palpable draining ... rakari #clinical #photo ... #skinrash #dermatology
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