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differential hematology management vasculitis clinical skinrash activation apml classification dermatologic differentiation eschar gpa granulomatosis hand hemophagocytic hlh joint lcv leukocytoclastic
Skin Conditions Associated with Joint Pain Rash • Human parvovirus B19 infection Malar rash • SLE • Human parvovirus B19 infection •
• Rheumatic fever ... Crohn's disease Palpable ... Sarcoidosis #dermatology ... #differential #diagnosis ... #rheumatology
Purpura - Differential Diagnosis Framework Non-blanchable, dark red to purple, hemorrhagic skin lesions that result from leakage
- Differential Diagnosis ... Kasabach-Merritt syndrome ... mountain spotted fever ... #hematology #rheumatology ... #dermatology
Macrophage Activation Syndrome (MAS) Classified among the secondary or acquired forms of haemophagocytic lymphohistiocytosis (sHLH) What? A subset of
disease • Periodic fever ... - Nonremitting fever ... Petechial or purpuric rash ... #Diagnosis #Management ... #Hematology #Rheumatology
Dermatologic Manifestations of Granulomatosis with Polyangiitis (GPA) Skin involvement in granulomatosis with polyangiitis (GPA) is common and
• Petechiae, Palpable ... Maculopapular rash ... • Goodpasture syndrome ... #rash #diagnosis ... #rheumatology
Vasculitis - Differential Diagnosis Framework When to Consider Vasculitis: • Purpura, ischemic skin lesions • Mononeuritis multiplex • Hematuria, proteinuria,
- Differential Diagnosis ... Vasculitis: • Fevers ... and branches • Fever ... , mucositis • Rash ... #Rheumatology
Rickettsialpox Eschar 40 homeless male from NY admitted with fever, chills, headache, myalgias. Diagnosis? Rickettsialpox R akari classic
Diagnosis? ... Palpable draining ... of R akari is macrophage ... rakari #clinical #photo ... #skinrash #dermatology
Hemophagocytic Lymphohistiocytosis (HLH) Definition: Overwhelming clinical syndrome associated with excessive macrophage activation and cytokine storm due to
Overwhelming clinical syndrome ... with excessive macrophage ... Diagnosis via genetic ... following: • Fever ... management #treatment #hematology
Vasculitis and Vasculitides - Differential Diagnosis Framework When to Consider Vasculitis: • Purpura, ischemic skin lesions •
mucositis - Rash ... Vasculitis: • Fevers ... scleritis • Palpable ... Skin -> causing palpable ... #rheumatology #
Differentiation Syndrome in APML Epidemiology: • Incidence: common in APL (2-48% depending on the study) • Triggers:
Differentiation Syndrome ... Subacute-Acute: • Common: fever ... Imaging: CXR- pulmonary ... Differentiation #Syndrome ... #management #hematology
Vancomycin induced Leukocytoclastic Vasculitis (LCV) of the Hand 70 M vertebral osteomyelitis on vancomycin and cefepime for
Presents with diffuse palpable ... rash. ... Diagnosis? ... Hand #skinrash #dermatology ... #clinical #photo
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