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differential hiv management associated bee criteria dementia disorder encephalopathy infections infectiousdiseases mcdonald ms multiple myelitis neurocognitive noninflammatory opportunistic posterior pres
CNS Ring-Enhancing Lesions - Immunocompromised vs Immunocompetent Multiple Ring-Enhancing Lesions: • Toxoplasmosis (CD4 < 100) • Other
Compatible syndrome + MRI ... lesions + toxo ... #Brain #differential ... #diagnosis #causes ... #radiology #neurology
McDonald Criteria for Diagnosis of Multiple Sclerosis • 2 or more attacks, 2 or more lesions
attacks, 2 or more lesions ... more attacks, 1 lesion ... • 1 attack, 2 lesions ... • 1 attack, 1 lesion ... #neurology
CNS Infection in HIV / AIDS - Differential Diagnosis Framework Principles of HIV-Associated CNS Opportunistic Infections: •
Imaging: - MRI ... parietal - Size lesions ... Demyelinating disease caused ... Enhancement: multifocal lesions ... punched-out" cystic lesions
HIV-Associated Neurocognitive Disorder (HAND) Definition: HIV-Associated Neurocognitive disorders categories: • Asymptomatic neurocognitive impairment • Mild neurocognitive impairment • HIV dementia Pathophysiology: HIV frequently
bilateral white matter lesions ... well-defined than PML lesions ... Diagnosis: MRI ... disorder #dementia #AIDS ... #Neurology
Transverse Myelitis Overview Focal inflammatory disorder of the spinal cord resulting in rapid onset of weakness, sensory
that results in CNS ... compressive cord lesion ... less swollen - Lesion ... brain and/or optic ... nerve lesions suggestive
BEE Syndromes - Non-inflammatory Causes Immune-mediated conditions affecting the Brain, Eye, and Ear Visual or auditory symptoms in
affecting the Brain ... nervous system (CNS ... neuropathy (LHON) plus MRI ... lesions and clinical ... BEE #Syndromes #neurology
Posterior Reversible Encephalopathy Syndrome (PRES) Overview Clinico-Radiological Syndrome, characterized by: • Headache • Seizures • Altered mental
parietal lobes of the brain ... may precede the neurologic ... showing cortical lesions ... the underlying cause ... Seizures: Treat with AEDs
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