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signs rheumatology pathophysiology dermatology differential disease management syndrome vasculitis antimda5 antimda5dm autoimmune behcet clinical crest criteria dermatomyositis gca giantcell kawasaki
CREST Syndrome: Pathogenesis and Clinical Findings CALCINOSIS (BB-sized, hard nodules in fingers) RAYNAUD'S Phenomenon ESOPHAGEAL DYSMOTILITY SCLERODACTYLY (thickening and tightening
tightening of skin ... (In face, hands ... distal to MCPs ... Pathophysiology #Diagnosis ... #Signs #Symptoms
Reactive Arthritis • Inflammation of joints (commonly large joints) - Asymmetric Oligoarthritis: Joint
Reactive Arthritis ... Transient • Skin ... keratotic lesions on hands ... pathophysiology #diagnosis ... #signs #symptoms
Behçet's Syndrome Systemic disease associated with inflammation of multiple organs, small-vessel vasculitis and large-vessel vasculopathy Epidemiology: • Young
response to local skin ... meningitis), MCC CNS symptoms ... test (this is a skin ... inhibitors • Uveitis- Ophthalmology ... management #signs #symptoms
Giant cell arteritis (GCA) Giant cell arteritis (GCA) definition: Most common systemic inflammatory vasculitis in older adults
variably: On one hand ... required due to skip ... required +/- prompt ophthalmology ... absence of visual symptoms ... Temporal #Signs #Symptoms
ANTI-MDA5 DERMATOMYOSITIS Cutaneous manifestations: • Periorbital heliotrope (blue-purple) rash with edema • Erythematous rash on the face, or the
dorsal part of the MCP ... fingertips ("mechanic’s hands ... • Arthralgia/arthritis ... • Mechanic's hands ... #dermatology #diagnosis
Vasculitis - Differential Diagnosis Framework When to Consider Vasculitis: • Purpura, ischemic skin lesions • Mononeuritis multiplex • Hematuria, proteinuria,
- Differential Diagnosis ... Vasculitis Differential Diagnosis ... Presentation: Systemic Symptoms ... • Progressive symptoms ... occasional oligoclonal bands
Kawasaki Disease: Clinical Findings Diagnostic Criteria - Fever and 4/5 of the following: • Conjunctivitis • Polymorphous
Clinical Findings Diagnostic ... Edema/erythema on hands ... feet Signs/Symptoms ... : - Coronary Arteritis ... - Generalized Skin
Secondary Syphilis Rash Secondary syphilis is the most contagious of all the stages of this disease, and
Skin rash and malaise ... The signs and symptoms ... the palms of the hands ... Syphilis #Rash #Diagnosis ... #Clinical #Photo
Autoimmune Myositis - Differential Diagnosis Framework Inflammatory Myopathies: Commonly symmetric proximal muscle weakness, no substantial muscle pain
- Differential Diagnosis ... myopathies Diagnostic ... ) • Anti-Mi2 (skin ... • Nonerosive arthritis ... • Mechanic's hands
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